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The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.
Wilson NK, Miranda-Saavedra D, Kinston S, Bonadies N, Foster SD, Calero-Nieto F, Dawson MA, Donaldson IJ, Dumon S, Frampton J, Janky R, Sun XH, Teichmann SA, Bannister AJ, Göttgens B. Wilson NK, et al. Among authors: gottgens b. Blood. 2009 May 28;113(22):5456-65. doi: 10.1182/blood-2009-01-200048. Epub 2009 Apr 3. Blood. 2009. PMID: 19346495 Free article.
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.
Dawson MA, Bannister AJ, Göttgens B, Foster SD, Bartke T, Green AR, Kouzarides T. Dawson MA, et al. Among authors: gottgens b. Nature. 2009 Oct 8;461(7265):819-22. doi: 10.1038/nature08448. Epub 2009 Sep 27. Nature. 2009. PMID: 19783980 Free PMC article.
Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.
Wilson NK, Timms RT, Kinston SJ, Cheng YH, Oram SH, Landry JR, Mullender J, Ottersbach K, Gottgens B. Wilson NK, et al. Among authors: gottgens b. Mol Cell Biol. 2010 Aug;30(15):3853-63. doi: 10.1128/MCB.00032-10. Epub 2010 Jun 1. Mol Cell Biol. 2010. PMID: 20516218 Free PMC article.
Three distinct patterns of histone H3Y41 phosphorylation mark active genes.
Dawson MA, Foster SD, Bannister AJ, Robson SC, Hannah R, Wang X, Xhemalce B, Wood AD, Green AR, Göttgens B, Kouzarides T. Dawson MA, et al. Among authors: gottgens b. Cell Rep. 2012 Sep 27;2(3):470-7. doi: 10.1016/j.celrep.2012.08.016. Epub 2012 Sep 20. Cell Rep. 2012. PMID: 22999934 Free PMC article.
324 results