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Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease.
Gulbins A, Horstmann M, Daser A, Flögel U, Oeverhaus M, Bechrakis NE, Banga JP, Keitsch S, Wilker B, Krause G, Hammer GD, Spencer AG, Zeidan R, Eckstein A, Philipp S, Görtz GE. Gulbins A, et al. Among authors: gortz ge. Front Endocrinol (Lausanne). 2023 Jun 26;14:1211473. doi: 10.3389/fendo.2023.1211473. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37435490 Free PMC article.
Comparative Assessment of Female Mouse Model of Graves' Orbitopathy Under Different Environments, Accompanied by Proinflammatory Cytokine and T-Cell Responses to Thyrotropin Hormone Receptor Antigen.
Berchner-Pfannschmidt U, Moshkelgosha S, Diaz-Cano S, Edelmann B, Görtz GE, Horstmann M, Noble A, Hansen W, Eckstein A, Banga JP. Berchner-Pfannschmidt U, et al. Among authors: gortz ge. Endocrinology. 2016 Apr;157(4):1673-82. doi: 10.1210/en.2015-1829. Epub 2016 Feb 12. Endocrinology. 2016. PMID: 26872090
Graves' orbitopathy occurs sex-independently in an autoimmune hyperthyroid mouse model.
Schlüter A, Flögel U, Diaz-Cano S, Görtz GE, Stähr K, Oeverhaus M, Plöhn S, Mattheis S, Moeller LC, Lang S, Bechrakis NE, Banga JP, Eckstein A, Berchner-Pfannschmidt U. Schlüter A, et al. Among authors: gortz ge. Sci Rep. 2018 Aug 30;8(1):13096. doi: 10.1038/s41598-018-31253-4. Sci Rep. 2018. PMID: 30166557 Free PMC article.
An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy.
Philipp S, Horstmann M, Hose M, Daser A, Görtz GE, Jesenek C, Flögel U, Hansen W, Bechrakis N, Banga JPS, Eckstein A, Berchner-Pfannschmidt U. Philipp S, et al. Among authors: gortz ge. Thyroid. 2022 Mar;32(3):283-293. doi: 10.1089/thy.2021.0464. Epub 2022 Jan 11. Thyroid. 2022. PMID: 34779257
Sphingolipids in thyroid eye disease.
Gulbins A, Görtz GE, Gulbins E, Eckstein A. Gulbins A, et al. Among authors: gortz ge. Front Endocrinol (Lausanne). 2023 Apr 4;14:1170884. doi: 10.3389/fendo.2023.1170884. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37082124 Free PMC article. Review.
12 results