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The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells.
Mengeste AM, Lund J, Katare P, Ghobadi R, Bakke HG, Lunde PK, Eide L, Mahony GO, Göpel S, Peng XR, Kase ET, Thoresen GH, Rustan AC. Mengeste AM, et al. Among authors: gopel s. Curr Res Pharmacol Drug Discov. 2021 Sep 28;2:100060. doi: 10.1016/j.crphar.2021.100060. eCollection 2021. Curr Res Pharmacol Drug Discov. 2021. PMID: 34909682 Free PMC article.
Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
Oshima M, Pechberty S, Bellini L, Göpel SO, Campana M, Rouch C, Dairou J, Cosentino C, Fantuzzi F, Toivonen S, Marchetti P, Magnan C, Cnop M, Le Stunff H, Scharfmann R. Oshima M, et al. Among authors: gopel so. Diabetologia. 2020 Feb;63(2):395-409. doi: 10.1007/s00125-019-05046-x. Epub 2019 Dec 3. Diabetologia. 2020. PMID: 31796987 Free PMC article.
High throughput generation of a resource of the human secretome in mammalian cells.
Tegel H, Dannemeyer M, Kanje S, Sivertsson Å, Berling A, Svensson AS, Hober A, Enstedt H, Volk AL, Lundqvist M, Moradi M, Afshari D, Ekblad S, Xu L, Westin M, Bidad F, Schiavone LH, Davies R, Mayr LM, Knight S, Göpel SO, Voldborg BG, Edfors F, Forsström B, von Feilitzen K, Zwahlen M, Rockberg J, Takanen JO, Uhlén M, Hober S. Tegel H, et al. Among authors: gopel so. N Biotechnol. 2020 Sep 25;58:45-54. doi: 10.1016/j.nbt.2020.05.002. Epub 2020 Jun 2. N Biotechnol. 2020. PMID: 32502629 Free article.
Hyperglucagonemia in youth is associated with high plasma free fatty acids, visceral adiposity, and impaired glucose tolerance.
Manell H, Kristinsson H, Kullberg J, Ubhayasekera SJK, Mörwald K, Staaf J, Cadamuro J, Zsoldos F, Göpel S, Sargsyan E, Ahlström H, Bergquist J, Weghuber D, Forslund A, Bergsten P. Manell H, et al. Among authors: gopel s. Pediatr Diabetes. 2019 Nov;20(7):880-891. doi: 10.1111/pedi.12890. Epub 2019 Jul 17. Pediatr Diabetes. 2019. PMID: 31271247
84 results