Göhlmann HW - Search Results

1

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.

Andries K, Verhasselt P, Guillemont J, Göhlmann HW, Neefs JM, Winkler H, Van Gestel J, Timmerman P, Zhu M, Lee E, Williams P, de Chaffoy D, Huitric E, Hoffner S, Cambau E, Truffot-Pernot C, Lounis N, Jarlier V. Andries K, et al. Among authors: gohlmann hw. Science. 2005 Jan 14;307(5707):223-7. doi: 10.1126/science.1106753. Epub 2004 Dec 9. Science. 2005. PMID: 15591164 Clinical Trial.

2

Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis.

Koul A, Vranckx L, Dendouga N, Balemans W, Van den Wyngaert I, Vergauwen K, Göhlmann HWH, Willebrords R, Poncelet A, Guillemont J, Bald D, Andries K. Koul A, et al. J Biol Chem. 2008 Sep 12;283(37):25273-25280. doi: 10.1074/jbc.M803899200. Epub 2008 Jul 14. J Biol Chem. 2008. PMID: 18625705 Free article.

3

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism.

Koul A, Vranckx L, Dhar N, Göhlmann HW, Özdemir E, Neefs JM, Schulz M, Lu P, Mørtz E, McKinney JD, Andries K, Bald D. Koul A, et al. Among authors: gohlmann hw. Nat Commun. 2014 Feb 26;5:3369. doi: 10.1038/ncomms4369. Nat Commun. 2014. PMID: 24569628 Free PMC article.

4

Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines.

Cox MJ, Jaensch S, Van de Waeter J, Cougnaud L, Seynaeve D, Benalla S, Koo SJ, Van Den Wyngaert I, Neefs JM, Malkov D, Bittremieux M, Steemans M, Peeters PJ, Wegner JK, Ceulemans H, Gustin E, Chong YT, Göhlmann HWH. Cox MJ, et al. Among authors: gohlmann hwh. Sci Rep. 2020 Aug 6;10(1):13262. doi: 10.1038/s41598-020-69354-8. Sci Rep. 2020. PMID: 32764586 Free PMC article.

5

Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout.

Versele M, Talloen W, Rockx C, Geerts T, Janssen B, Lavrijssen T, King P, Göhlmann HW, Page M, Perera T. Versele M, et al. Among authors: gohlmann hw. Mol Cancer Ther. 2009 Jul;8(7):1846-55. doi: 10.1158/1535-7163.MCT-08-1029. Epub 2009 Jul 7. Mol Cancer Ther. 2009. PMID: 19584230

6

Transcriptional response to corticotropin-releasing factor in AtT-20 cells.

Peeters PJ, Göhlmann HW, Van den Wyngaert I, Swagemakers SM, Bijnens L, Kass SU, Steckler T. Peeters PJ, et al. Among authors: gohlmann hw. Mol Pharmacol. 2004 Nov;66(5):1083-92. doi: 10.1124/mol.104.000950. Epub 2004 Jul 22. Mol Pharmacol. 2004. PMID: 15272051

7

Molecular profiling of murine sensory neurons in the nodose and dorsal root ganglia labeled from the peritoneal cavity.

Peeters PJ, Aerssens J, de Hoogt R, Stanisz A, Göhlmann HW, Hillsley K, Meulemans A, Grundy D, Stead RH, Coulie B. Peeters PJ, et al. Among authors: gohlmann hw. Physiol Genomics. 2006 Feb 14;24(3):252-63. doi: 10.1152/physiolgenomics.00169.2005. Epub 2005 Nov 22. Physiol Genomics. 2006. PMID: 16303873

8

Microarray profiling of DNA extracted from FFPE tissues using SNP 6.0 Affymetrix platform.

Tuefferd M, de Bondt A, Van den Wyngaert I, Talloen W, Göhlmann H. Tuefferd M, et al. Methods Mol Biol. 2011;724:147-60. doi: 10.1007/978-1-61779-055-3_10. Methods Mol Biol. 2011. PMID: 21370012

9

Alterations in the brain-gut axis underlying visceral chemosensitivity in Nippostrongylus brasiliensis-infected mice.

Aerssens J, Hillsley K, Peeters PJ, de Hoogt R, Stanisz A, Lin JH, Van den Wyngaert I, Göhlmann HW, Grundy D, Stead RH, Coulie B. Aerssens J, et al. Among authors: gohlmann hw. Gastroenterology. 2007 Apr;132(4):1375-87. doi: 10.1053/j.gastro.2007.02.019. Epub 2007 Feb 7. Gastroenterology. 2007. PMID: 17408648

10

High-Throughput Gene Expression Profiles to Define Drug Similarity and Predict Compound Activity.

De Wolf H, Cougnaud L, Van Hoorde K, De Bondt A, Wegner JK, Ceulemans H, Göhlmann H. De Wolf H, et al. Assay Drug Dev Technol. 2018 Apr;16(3):162-176. doi: 10.1089/adt.2018.845. Assay Drug Dev Technol. 2018. PMID: 29658791

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