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IκBα targeting promotes oxidative stress-dependent cell death.
Carrà G, Ermondi G, Riganti C, Righi L, Caron G, Menga A, Capelletto E, Maffeo B, Lingua MF, Fusella F, Volante M, Taulli R, Guerrasio A, Novello S, Brancaccio M, Piazza R, Morotti A. Carrà G, et al. Among authors: fusella f. J Exp Clin Cancer Res. 2021 Apr 16;40(1):136. doi: 10.1186/s13046-021-01921-x. J Exp Clin Cancer Res. 2021. PMID: 33863364 Free PMC article.
Targeting the Extracellular HSP90 Co-Chaperone Morgana Inhibits Cancer Cell Migration and Promotes Anticancer Immunity.
Seclì L, Avalle L, Poggio P, Fragale G, Cannata C, Conti L, Iannucci A, Carrà G, Rubinetto C, Miniscalco B, Hirsch E, Poli V, Morotti A, De Andrea M, Turco E, Cavallo F, Fusella F, Brancaccio M. Seclì L, et al. Among authors: fusella f. Cancer Res. 2021 Sep 15;81(18):4794-4807. doi: 10.1158/0008-5472.CAN-20-3150. Epub 2021 Jun 30. Cancer Res. 2021. PMID: 34193441
The one thousand and one chaperones of the NF-κB pathway.
Fusella F, Seclì L, Cannata C, Brancaccio M. Fusella F, et al. Cell Mol Life Sci. 2020 Jun;77(12):2275-2288. doi: 10.1007/s00018-019-03402-z. Epub 2019 Dec 6. Cell Mol Life Sci. 2020. PMID: 31811308 Free article. Review.
The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.
Fusella F, Seclì L, Busso E, Krepelova A, Moiso E, Rocca S, Conti L, Annaratone L, Rubinetto C, Mello-Grand M, Singh V, Chiorino G, Silengo L, Altruda F, Turco E, Morotti A, Oliviero S, Castellano I, Cavallo F, Provero P, Tarone G, Brancaccio M. Fusella F, et al. Nat Commun. 2017 Nov 21;8(1):1636. doi: 10.1038/s41467-017-01829-1. Nat Commun. 2017. PMID: 29158506 Free PMC article.
Morgana acts as an oncosuppressor in chronic myeloid leukemia.
Di Savino A, Panuzzo C, Rocca S, Familiari U, Piazza R, Crivellaro S, Carrà G, Ferretti R, Fusella F, Giugliano E, Camporeale A, Franco I, Miniscalco B, Cutrin JC, Turco E, Silengo L, Hirsch E, Rege-Cambrin G, Gambacorti-Passerini C, Pandolfi PP, Papotti M, Saglio G, Tarone G, Morotti A, Brancaccio M. Di Savino A, et al. Among authors: fusella f. Blood. 2015 Apr 2;125(14):2245-53. doi: 10.1182/blood-2014-05-575001. Epub 2015 Feb 12. Blood. 2015. PMID: 25678499 Free article.
The double face of Morgana in tumorigenesis.
Brancaccio M, Rocca S, Seclì L, Busso E, Fusella F. Brancaccio M, et al. Among authors: fusella f. Oncotarget. 2015 Dec 15;6(40):42603-12. doi: 10.18632/oncotarget.6058. Oncotarget. 2015. PMID: 26460959 Free PMC article. Review.
The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.
Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P. Grasso S, et al. Among authors: fusella f. Cell Death Differ. 2020 Feb;27(2):790-807. doi: 10.1038/s41418-019-0386-6. Epub 2019 Jul 8. Cell Death Differ. 2020. PMID: 31285546 Free PMC article.
Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway.
Fusella F, Ferretti R, Recupero D, Rocca S, Di Savino A, Tornillo G, Silengo L, Turco E, Cabodi S, Provero P, Pandolfi PP, Sapino A, Tarone G, Brancaccio M. Fusella F, et al. J Pathol. 2014 Oct;234(2):152-63. doi: 10.1002/path.4341. Epub 2014 Aug 6. J Pathol. 2014. PMID: 24615293
16 results