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Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency.
Kim O, Butler M, Sergi Z, Robey RW, Zhang M, Chari R, Pang Y, Yu G, Zhang W, Song H, Davis D, Hawley RG, Wen X, Wang H, Quezado M, Tran B, Merchant M, Ranjan A, Furnari FB, Khan J, Gilbert MR, Ryan Miller C, Gottesman MM, Pommier Y, Wu J. Kim O, et al. Among authors: furnari fb. Neurooncol Adv. 2023 Aug 21;5(1):vdad102. doi: 10.1093/noajnl/vdad102. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 37706203 Free PMC article.
EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.
Feng H, Lopez GY, Kim CK, Alvarez A, Duncan CG, Nishikawa R, Nagane M, Su AJ, Auron PE, Hedberg ML, Wang L, Raizer JJ, Kessler JA, Parsa AT, Gao WQ, Kim SH, Minata M, Nakano I, Grandis JR, McLendon RE, Bigner DD, Lin HK, Furnari FB, Cavenee WK, Hu B, Yan H, Cheng SY. Feng H, et al. Among authors: furnari fb. J Clin Invest. 2014 Sep;124(9):3741-56. doi: 10.1172/JCI73093. Epub 2014 Jul 25. J Clin Invest. 2014. PMID: 25061874 Free PMC article.
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
Tsuchihashi K, Okazaki S, Ohmura M, Ishikawa M, Sampetrean O, Onishi N, Wakimoto H, Yoshikawa M, Seishima R, Iwasaki Y, Morikawa T, Abe S, Takao A, Shimizu M, Masuko T, Nagane M, Furnari FB, Akiyama T, Suematsu M, Baba E, Akashi K, Saya H, Nagano O. Tsuchihashi K, et al. Among authors: furnari fb. Cancer Res. 2016 May 15;76(10):2954-63. doi: 10.1158/0008-5472.CAN-15-2121. Epub 2016 Mar 15. Cancer Res. 2016. PMID: 26980765 Free PMC article.
A drosophila model for EGFR-Ras and PI3K-dependent human glioma.
Read RD, Cavenee WK, Furnari FB, Thomas JB. Read RD, et al. Among authors: furnari fb. PLoS Genet. 2009 Feb;5(2):e1000374. doi: 10.1371/journal.pgen.1000374. Epub 2009 Feb 13. PLoS Genet. 2009. PMID: 19214224 Free PMC article.
136 results