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137 results

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Page 1
Circular ecDNA promotes accessible chromatin and high oncogene expression.
Wu S, Turner KM, Nguyen N, Raviram R, Erb M, Santini J, Luebeck J, Rajkumar U, Diao Y, Li B, Zhang W, Jameson N, Corces MR, Granja JM, Chen X, Coruh C, Abnousi A, Houston J, Ye Z, Hu R, Yu M, Kim H, Law JA, Verhaak RGW, Hu M, Furnari FB, Chang HY, Ren B, Bafna V, Mischel PS. Wu S, et al. Among authors: furnari fb. Nature. 2019 Nov;575(7784):699-703. doi: 10.1038/s41586-019-1763-5. Epub 2019 Nov 20. Nature. 2019. PMID: 31748743 Free PMC article.
Corrigendum to: EGFR, the Lazarus target for precision oncology in glioblastoma.
Lin B, Ziebro J, Smithberger E, Skinner KR, Zhao E, Cloughesy TF, Binder ZA, O'Rourke DM, Nathanson DA, Furnari FB, Miller CR. Lin B, et al. Among authors: furnari fb. Neuro Oncol. 2023 Jan 5;25(1):213. doi: 10.1093/neuonc/noac254. Neuro Oncol. 2023. PMID: 36416495 Free PMC article. No abstract available.
Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars.
Skinner KR, Koga T, Miki S, Gruener RF, Grigore FN, Torii EH, Seelig DM, Suzuki Y, Kawauchi D, Lin B, Malicki DM, Chen CC, Benveniste EN, Patel RP, McFarland BC, Huang RS, Jones C, Mackay A, Miller CR, Furnari FB. Skinner KR, et al. Among authors: furnari fb. bioRxiv [Preprint]. 2023 Feb 24:2023.02.24.528982. doi: 10.1101/2023.02.24.528982. bioRxiv. 2023. PMID: 36865329 Free PMC article. Preprint.
Caspase-8 as a novel mediator linking Src kinase signaling to enhanced glioblastoma malignancy.
Contadini C, Ferri A, Di Martile M, Cirotti C, Del Bufalo D, De Nicola F, Pallocca M, Fanciulli M, Sacco F, Donninelli G, Capone A, Volpe E, Keller N, Miki S, Kawauchi D, Stupack D, Furnari F, Barilà D. Contadini C, et al. Cell Death Differ. 2023 Feb;30(2):417-428. doi: 10.1038/s41418-022-01093-x. Epub 2022 Dec 2. Cell Death Differ. 2023. PMID: 36460775 Free PMC article.
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.
Fenton TR, Nathanson D, Ponte de Albuquerque C, Kuga D, Iwanami A, Dang J, Yang H, Tanaka K, Oba-Shinjo SM, Uno M, Inda MM, Wykosky J, Bachoo RM, James CD, DePinho RA, Vandenberg SR, Zhou H, Marie SK, Mischel PS, Cavenee WK, Furnari FB. Fenton TR, et al. Among authors: furnari fb. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14164-9. doi: 10.1073/pnas.1211962109. Epub 2012 Aug 13. Proc Natl Acad Sci U S A. 2012. PMID: 22891331 Free PMC article.
PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies.
Iwanami A, Gini B, Zanca C, Matsutani T, Assuncao A, Nael A, Dang J, Yang H, Zhu S, Kohyama J, Kitabayashi I, Cavenee WK, Cloughesy TF, Furnari FB, Nakamura M, Toyama Y, Okano H, Mischel PS. Iwanami A, et al. Among authors: furnari fb. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4339-44. doi: 10.1073/pnas.1217602110. Epub 2013 Feb 25. Proc Natl Acad Sci U S A. 2013. PMID: 23440206 Free PMC article. Clinical Trial.
A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.
Read RD, Fenton TR, Gomez GG, Wykosky J, Vandenberg SR, Babic I, Iwanami A, Yang H, Cavenee WK, Mischel PS, Furnari FB, Thomas JB. Read RD, et al. Among authors: furnari fb. PLoS Genet. 2013;9(2):e1003253. doi: 10.1371/journal.pgen.1003253. Epub 2013 Feb 14. PLoS Genet. 2013. PMID: 23459592 Free PMC article.
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.
Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, Gomez G, Eskin A, Hwang K, Wang J, Masui K, Paucar A, Yang H, Ohashi M, Zhu S, Wykosky J, Reed R, Nelson SF, Cloughesy TF, James CD, Rao PN, Kornblum HI, Heath JR, Cavenee WK, Furnari FB, Mischel PS. Nathanson DA, et al. Among authors: furnari fb. Science. 2014 Jan 3;343(6166):72-6. doi: 10.1126/science.1241328. Epub 2013 Dec 5. Science. 2014. PMID: 24310612 Free PMC article.
137 results