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Chronic inflammation in the etiology of disease across the life span.
Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW, Fasano A, Miller GW, Miller AH, Mantovani A, Weyand CM, Barzilai N, Goronzy JJ, Rando TA, Effros RB, Lucia A, Kleinstreuer N, Slavich GM. Furman D, et al. Nat Med. 2019 Dec;25(12):1822-1832. doi: 10.1038/s41591-019-0675-0. Epub 2019 Dec 5. Nat Med. 2019. PMID: 31806905 Free PMC article. Review.
SARS-CoV-2, COVID-19 and the Ageing Immune System.
Bartleson JM, Radenkovic D, Covarrubias AJ, Furman D, Winer DA, Verdin E. Bartleson JM, et al. Among authors: furman d. Nat Aging. 2021 Sep;1(9):769-782. doi: 10.1038/s43587-021-00114-7. Epub 2021 Sep 14. Nat Aging. 2021. PMID: 34746804 Free PMC article.
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging.
Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, Shen-Orr SS, Maecker HT, Dekker CL, Wyss-Coray T, Franceschi C, Jojic V, Haddad F, Montoya JG, Wu JC, Davis MM, Furman D. Sayed N, et al. Among authors: furman d. Nat Aging. 2021 Jul;1:598-615. doi: 10.1038/s43587-021-00082-y. Epub 2021 Jul 12. Nat Aging. 2021. PMID: 34888528 Free PMC article.
Age-related brain atrophy is not a homogenous process: Different functional brain networks associate differentially with aging and blood factors.
Markov NT, Lindbergh CA, Staffaroni AM, Perez K, Stevens M, Nguyen K, Murad NF, Fonseca C, Campisi J, Kramer J, Furman D. Markov NT, et al. Among authors: furman d. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2207181119. doi: 10.1073/pnas.2207181119. Epub 2022 Dec 2. Proc Natl Acad Sci U S A. 2022. PMID: 36459652 Free PMC article.
Author Correction: An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging.
Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, Shen-Orr SS, Maecker HT, Dekker CL, Wyss-Coray T, Franceschi C, Jojic V, Haddad F, Montoya JG, Wu JC, Davis MM, Furman D. Sayed N, et al. Among authors: furman d. Nat Aging. 2021 Aug;1(8):748. doi: 10.1038/s43587-021-00102-x. Nat Aging. 2021. PMID: 37117770 No abstract available.
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
Furman D, Chang J, Lartigue L, Bolen CR, Haddad F, Gaudilliere B, Ganio EA, Fragiadakis GK, Spitzer MH, Douchet I, Daburon S, Moreau JF, Nolan GP, Blanco P, Déchanet-Merville J, Dekker CL, Jojic V, Kuo CJ, Davis MM, Faustin B. Furman D, et al. Nat Med. 2017 Feb;23(2):174-184. doi: 10.1038/nm.4267. Epub 2017 Jan 16. Nat Med. 2017. PMID: 28092664 Free PMC article.
A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring.
Alpert A, Pickman Y, Leipold M, Rosenberg-Hasson Y, Ji X, Gaujoux R, Rabani H, Starosvetsky E, Kveler K, Schaffert S, Furman D, Caspi O, Rosenschein U, Khatri P, Dekker CL, Maecker HT, Davis MM, Shen-Orr SS. Alpert A, et al. Among authors: furman d. Nat Med. 2019 Mar;25(3):487-495. doi: 10.1038/s41591-019-0381-y. Epub 2019 Mar 6. Nat Med. 2019. PMID: 30842675 Free PMC article.
Systems immunology: just getting started.
Davis MM, Tato CM, Furman D. Davis MM, et al. Among authors: furman d. Nat Immunol. 2017 Jun 20;18(7):725-732. doi: 10.1038/ni.3768. Nat Immunol. 2017. PMID: 28632713 Free PMC article. Review.
167 results