Furkert D - Search Results

1

Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling.

Qi J, Cheng W, Gao Z, Chen Y, Shipton ML, Furkert D, Chin AC, Riley AM, Fiedler D, Potter BVL, Fu C. Qi J, et al. Among authors: furkert d. Biomed Pharmacother. 2023 May;161:114449. doi: 10.1016/j.biopha.2023.114449. Epub 2023 Feb 27. Biomed Pharmacother. 2023. PMID: 36857911 Free PMC article.

2

Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome.

Furkert D, Hostachy S, Nadler-Holly M, Fiedler D. Furkert D, et al. Cell Chem Biol. 2020 Aug 20;27(8):1097-1108.e4. doi: 10.1016/j.chembiol.2020.07.017. Epub 2020 Aug 11. Cell Chem Biol. 2020. PMID: 32783964 Free article.

3

IP₇-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery.

Desmarini D, Lev S, Furkert D, Crossett B, Saiardi A, Kaufman-Francis K, Li C, Sorrell TC, Wilkinson-White L, Matthews J, Fiedler D, Djordjevic JT. Desmarini D, et al. Among authors: furkert d. mBio. 2020 Oct 20;11(5):e01920-20. doi: 10.1128/mBio.01920-20. mBio. 2020. PMID: 33082258 Free PMC article.

4

The inositol pyrophosphate 5-InsP₇ drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α.

Chin AC, Gao Z, Riley AM, Furkert D, Wittwer C, Dutta A, Rojas T, Semenza ER, Felder RA, Pluznick JL, Jessen HJ, Fiedler D, Potter BVL, Snyder SH, Fu C. Chin AC, et al. Among authors: furkert d. Sci Adv. 2020 Oct 28;6(44):eabb8542. doi: 10.1126/sciadv.abb8542. Print 2020 Oct. Sci Adv. 2020. PMID: 33115740 Free PMC article.

5

Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes.

Furkert D, Nadler-Holly M, Fiedler D. Furkert D, et al. STAR Protoc. 2021 Jan 14;2(1):100277. doi: 10.1016/j.xpro.2020.100277. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33490990 Free PMC article.

6

Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs.

Hostachy S, Utesch T, Franke K, Dornan GL, Furkert D, Türkaydin B, Haucke V, Sun H, Fiedler D. Hostachy S, et al. Among authors: furkert d. Chem Sci. 2021 Jul 8;12(32):10696-10702. doi: 10.1039/d1sc02975d. eCollection 2021 Aug 18. Chem Sci. 2021. PMID: 34476054 Free PMC article.

7

Using Biotinylated myo-Inositol Hexakisphosphate to Investigate Inositol Pyrophosphate-Protein Interactions with Surface-Based Biosensors.

Couto D, Richter A, Walter H, Furkert D, Hothorn M, Fiedler D. Couto D, et al. Among authors: furkert d. Biochemistry. 2021 Sep 21;60(37):2739-2748. doi: 10.1021/acs.biochem.1c00497. Epub 2021 Sep 9. Biochemistry. 2021. PMID: 34499474 Free article.

8

Structural evidence for visual arrestin priming via complexation of phosphoinositols.

Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD. Sander CL, et al. Among authors: furkert d. Structure. 2022 Feb 3;30(2):263-277.e5. doi: 10.1016/j.str.2021.10.002. Epub 2021 Oct 21. Structure. 2022. PMID: 34678158 Free PMC article.

9

Versatile signaling mechanisms of inositol pyrophosphates.

Nguyen Trung M, Furkert D, Fiedler D. Nguyen Trung M, et al. Among authors: furkert d. Curr Opin Chem Biol. 2022 Oct;70:102177. doi: 10.1016/j.cbpa.2022.102177. Epub 2022 Jun 30. Curr Opin Chem Biol. 2022. PMID: 35780751 Free article. Review.

10

Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischemia-reperfusion injury by elevating plasma adiponectin.

Fu L, Du J, Furkert D, Shipton ML, Liu X, Aguirre T, Chin AC, Riley AM, Potter BVL, Fiedler D, Zhang X, Zhu Y, Fu C. Fu L, et al. Among authors: furkert d. Cardiovasc Res. 2024 Jan 22:cvae017. doi: 10.1093/cvr/cvae017. Online ahead of print. Cardiovasc Res. 2024. PMID: 38252884

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