Funke U - Search Results

1

New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET.

Vercouillie J, Deuther-Conrad W, Scheunemann M, Emond P, Fischer S, Funke U, Steinbach J, Guilloteau D, Brust P. Vercouillie J, et al. Among authors: funke u. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4991-5. doi: 10.1016/j.bmcl.2007.02.082. Epub 2007 Mar 7. Bioorg Med Chem Lett. 2007. PMID: 17658253

2

3-(4-(6-Fluoroalkoxy-3,4-dihydroisoquinoline-2(1H)-yl)cyclohexyl)-1H-indole-5-carbonitriles for SERT imaging: chemical synthesis, evaluation in vitro and radiofluorination.

Funke U, Fischer S, Hiller A, Scheunemann M, Deuther-Conrad W, Brust P, Steinbach J. Funke U, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4727-30. doi: 10.1016/j.bmcl.2008.06.077. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18644726

3

Automation of the radiosynthesis and purification procedures for [18F]Fluspidine preparation, a new radiotracer for clinical investigations in PET imaging of σ(1) receptors in brain.

Maisonial-Besset A, Funke U, Wenzel B, Fischer S, Holl K, Wünsch B, Steinbach J, Brust P. Maisonial-Besset A, et al. Among authors: funke u. Appl Radiat Isot. 2014 Feb;84:1-7. doi: 10.1016/j.apradiso.2013.10.015. Epub 2013 Nov 5. Appl Radiat Isot. 2014. PMID: 24291352

4

Fluorine-containing 6,7-dialkoxybiaryl-based inhibitors for phosphodiesterase 10 A: synthesis and in vitro evaluation of inhibitory potency, selectivity, and metabolism.

Schwan G, Barbar Asskar G, Höfgen N, Kubicova L, Funke U, Egerland U, Zahn M, Nieber K, Scheunemann M, Sträter N, Brust P, Briel D. Schwan G, et al. Among authors: funke u. ChemMedChem. 2014 Jul;9(7):1476-87. doi: 10.1002/cmdc.201300522. Epub 2014 Apr 11. ChemMedChem. 2014. PMID: 24729456

5

Assessment of α7 nicotinic acetylcholine receptor availability in juvenile pig brain with [¹⁸F]NS10743.

Deuther-Conrad W, Fischer S, Hiller A, Becker G, Cumming P, Xiong G, Funke U, Sabri O, Peters D, Brust P. Deuther-Conrad W, et al. Among authors: funke u. Eur J Nucl Med Mol Imaging. 2011 Aug;38(8):1541-9. doi: 10.1007/s00259-011-1808-y. Epub 2011 Apr 12. Eur J Nucl Med Mol Imaging. 2011. PMID: 21484373

6

Radiosynthesis and Radiotracer Properties of a 7-(2-[18F]Fluoroethoxy)-6-methoxypyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET.

Funke U, Deuther-Conrad W, Schwan G, Maisonial A, Scheunemann M, Fischer S, Hiller A, Briel D, Brust P. Funke U, et al. Pharmaceuticals (Basel). 2012 Feb 6;5(2):169-88. doi: 10.3390/ph5020169. Pharmaceuticals (Basel). 2012. PMID: 24288087 Free PMC article.

7

Radiosynthesis of racemic and enantiomerically pure (-)-[18F]flubatine--a promising PET radiotracer for neuroimaging of α4β2 nicotinic acetylcholine receptors.

Fischer S, Hiller A, Smits R, Hoepping A, Funke U, Wenzel B, Cumming P, Sabri O, Steinbach J, Brust P. Fischer S, et al. Among authors: funke u. Appl Radiat Isot. 2013 Apr;74:128-36. doi: 10.1016/j.apradiso.2013.01.002. Epub 2013 Jan 11. Appl Radiat Isot. 2013. PMID: 23416407

8

Use of 3-[(18)F]fluoropropanesulfonyl chloride as a prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides.

Löser R, Fischer S, Hiller A, Köckerling M, Funke U, Maisonial A, Brust P, Steinbach J. Löser R, et al. Among authors: funke u. Beilstein J Org Chem. 2013 May 27;9:1002-11. doi: 10.3762/bjoc.9.115. Print 2013. Beilstein J Org Chem. 2013. PMID: 23766817 Free PMC article.

9

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.

Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Villa A, et al. Among authors: funke u. Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018. Theranostics. 2018. PMID: 30555554 Free PMC article.

10

Identification of the allosteric P2X₇ receptor antagonist [¹¹C]SMW139 as a PET tracer of microglial activation.

Janssen B, Vugts DJ, Wilkinson SM, Ory D, Chalon S, Hoozemans JJM, Schuit RC, Beaino W, Kooijman EJM, van den Hoek J, Chishty M, Doméné A, Van der Perren A, Villa A, Maggi A, Molenaar GT, Funke U, Shevchenko RV, Baekelandt V, Bormans G, Lammertsma AA, Kassiou M, Windhorst AD. Janssen B, et al. Among authors: funke u. Sci Rep. 2018 Apr 26;8(1):6580. doi: 10.1038/s41598-018-24814-0. Sci Rep. 2018. PMID: 29700413 Free PMC article.

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