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A Fe2+-dependent self-inhibited state influences the druggability of human collagen lysyl hydroxylase (LH/PLOD) enzymes.
Scietti L, Moroni E, Mattoteia D, Fumagalli M, De Marco M, Negro L, Chiapparino A, Serapian SA, De Giorgi F, Faravelli S, Colombo G, Forneris F. Scietti L, et al. Among authors: fumagalli m. Front Mol Biosci. 2022 Aug 25;9:876352. doi: 10.3389/fmolb.2022.876352. eCollection 2022. Front Mol Biosci. 2022. PMID: 36090047 Free PMC article.
Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Burkholderia cenocepacia Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis Study.
Buroni S, Scoffone VC, Fumagalli M, Makarov V, Cagnone M, Trespidi G, De Rossi E, Forneris F, Riccardi G, Chiarelli LR. Buroni S, et al. Among authors: fumagalli m. Front Pharmacol. 2018 Jul 31;9:836. doi: 10.3389/fphar.2018.00836. eCollection 2018. Front Pharmacol. 2018. PMID: 30108505 Free PMC article.
616 results