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The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition.
Xiong C, Yang G, Kumar S, Aggarwal S, Leustik M, Snead C, Hamacher J, Fischer B, Umapathy NS, Hossain H, Wendel A, Catravas JD, Verin AD, Fulton D, Black SM, Chakraborty T, Lucas R. Xiong C, et al. Vascul Pharmacol. 2010 May-Jun;52(5-6):207-13. doi: 10.1016/j.vph.2009.12.010. Epub 2010 Jan 13. Vascul Pharmacol. 2010. PMID: 20074664 Free PMC article.
Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.
Lucas R, Yang G, Gorshkov BA, Zemskov EA, Sridhar S, Umapathy NS, Jezierska-Drutel A, Alieva IB, Leustik M, Hossain H, Fischer B, Catravas JD, Verin AD, Pittet JF, Caldwell RB, Mitchell TJ, Cederbaum SD, Fulton DJ, Matthay MA, Caldwell RW, Romero MJ, Chakraborty T. Lucas R, et al. Am J Respir Cell Mol Biol. 2012 Oct;47(4):445-53. doi: 10.1165/rcmb.2011-0332OC. Epub 2012 May 10. Am J Respir Cell Mol Biol. 2012. PMID: 22582175 Free PMC article.
LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.
Barabutis N, Handa V, Dimitropoulou C, Rafikov R, Snead C, Kumar S, Joshi A, Thangjam G, Fulton D, Black SM, Patel V, Catravas JD. Barabutis N, et al. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L883-93. doi: 10.1152/ajplung.00419.2012. Epub 2013 Apr 12. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23585225 Free PMC article.
240 results