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TP53 mutations confer resistance to hypomethylating agents and BCL-2 inhibition in myeloid neoplasms.
Blood Adv. 2022 Jun 14;6(11):3201-3206. doi: 10.1182/bloodadvances.2021005859.
Blood Adv. 2022.
PMID: 35026842
Free PMC article.
No abstract available.
Inhibitors of Bcl-2 and Bruton's tyrosine kinase synergize to abrogate diffuse large B-cell lymphoma growth in vitro and in orthotopic xenotransplantation models.
Bertram K, Leary PJ, Boudesco C, Fullin J, Stirm K, Dalal V, Zenz T, Tzankov A, Müller A.
Bertram K, et al. Among authors: fullin j.
Leukemia. 2022 Apr;36(4):1035-1047. doi: 10.1038/s41375-021-01470-4. Epub 2021 Nov 18.
Leukemia. 2022.
PMID: 34795418
Free PMC article.
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Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells.
Mueller J, Schimmer RR, Koch C, Schneiter F, Fullin J, Lysenko V, Pellegrino C, Klemm N, Russkamp N, Myburgh R, Volta L, Theocharides AP, Kurppa KJ, Ebert BL, Schroeder T, Manz MG, Boettcher S.
Mueller J, et al. Among authors: fullin j.
EMBO Mol Med. 2024 Mar;16(3):445-474. doi: 10.1038/s44321-024-00024-2. Epub 2024 Feb 14.
EMBO Mol Med. 2024.
PMID: 38355749
Free PMC article.
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Aging drives Tet2+/- clonal hematopoiesis via IL-1 signaling.
Caiado F, Kovtonyuk LV, Gonullu NG, Fullin J, Boettcher S, Manz MG.
Caiado F, et al. Among authors: fullin j.
Blood. 2023 Feb 23;141(8):886-903. doi: 10.1182/blood.2022016835.
Blood. 2023.
PMID: 36379023
Free PMC article.
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