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Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
Ichimura Y, Waguri S, Sou YS, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, Hoshii T, Hirao A, Takagi K, Mizushima T, Motohashi H, Lee MS, Yoshimori T, Tanaka K, Yamamoto M, Komatsu M. Ichimura Y, et al. Among authors: fukutomi t. Mol Cell. 2013 Sep 12;51(5):618-31. doi: 10.1016/j.molcel.2013.08.003. Epub 2013 Sep 5. Mol Cell. 2013. PMID: 24011591 Free article.
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.
Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T, Motohashi H, Waguri S, Soga T, Yamamoto M, Tanaka K, Komatsu M. Saito T, et al. Among authors: fukutomi t. Nat Commun. 2016 Jun 27;7:12030. doi: 10.1038/ncomms12030. Nat Commun. 2016. PMID: 27345495 Free PMC article.
The Keap1-Nrf2 system prevents onset of diabetes mellitus.
Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M. Uruno A, et al. Among authors: fukutomi t. Mol Cell Biol. 2013 Aug;33(15):2996-3010. doi: 10.1128/MCB.00225-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716596 Free PMC article.
Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice.
Hirotsu Y, Higashi C, Fukutomi T, Katsuoka F, Tsujita T, Yagishita Y, Matsuyama Y, Motohashi H, Uruno A, Yamamoto M. Hirotsu Y, et al. Among authors: fukutomi t. Genes Cells. 2014 Aug;19(8):650-65. doi: 10.1111/gtc.12165. Epub 2014 Jul 6. Genes Cells. 2014. PMID: 25041126 Free article.
HO-1 in lymph node metastasis predicted overall survival in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiation therapy.
Akaishi R, Fujishima F, Ishida H, Tsunokake J, Yamauchi T, Gokon Y, Ueki S, Fukutomi T, Okamoto H, Takaya K, Sato C, Taniyama Y, Nakamura T, Nakaya N, Kamei T, Sasano H. Akaishi R, et al. Among authors: fukutomi t. Cancer Rep (Hoboken). 2022 Mar;5(3):e1477. doi: 10.1002/cnr2.1477. Epub 2021 Jul 15. Cancer Rep (Hoboken). 2022. PMID: 34264023 Free PMC article.
361 results