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Semagacestat Is a Pseudo-Inhibitor of γ-Secretase.
Tagami S, Yanagida K, Kodama TS, Takami M, Mizuta N, Oyama H, Nishitomi K, Chiu YW, Okamoto T, Ikeuchi T, Sakaguchi G, Kudo T, Matsuura Y, Fukumori A, Takeda M, Ihara Y, Okochi M. Tagami S, et al. Among authors: fukumori a. Cell Rep. 2017 Oct 3;21(1):259-273. doi: 10.1016/j.celrep.2017.09.032. Cell Rep. 2017. PMID: 28978478 Free article.
FAD-linked presenilin-1 mutants impede translation regulation under ER stress.
Yasuda Y, Kudo T, Katayama T, Imaizumi K, Yatera M, Okochi M, Yamamori H, Matsumoto N, Kida T, Fukumori A, Okumura M, Tohyama M, Takeda M. Yasuda Y, et al. Among authors: fukumori a. Biochem Biophys Res Commun. 2002 Aug 16;296(2):313-8. doi: 10.1016/s0006-291x(02)00859-8. Biochem Biophys Res Commun. 2002. PMID: 12163019
Secretion of the Notch-1 Abeta-like peptide during Notch signaling.
Okochi M, Fukumori A, Jiang J, Itoh N, Kimura R, Steiner H, Haass C, Tagami S, Takeda M. Okochi M, et al. Among authors: fukumori a. J Biol Chem. 2006 Mar 24;281(12):7890-8. doi: 10.1074/jbc.M513250200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16434391 Free article.
Development of new screening system for Alzheimer disease, in vitro Abeta sink assay, to identify the dissociation of soluble Abeta from fibrils.
Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara T, Morishita R. Sato N, et al. Among authors: fukumori a. Neurobiol Dis. 2006 Jun;22(3):487-95. doi: 10.1016/j.nbd.2005.12.010. Epub 2006 Feb 20. Neurobiol Dis. 2006. PMID: 16488151
Altered localization of amyloid precursor protein under endoplasmic reticulum stress.
Kudo T, Okumura M, Imaizumi K, Araki W, Morihara T, Tanimukai H, Kamagata E, Tabuchi N, Kimura R, Kanayama D, Fukumori A, Tagami S, Okochi M, Kubo M, Tanii H, Tohyama M, Tabira T, Takeda M. Kudo T, et al. Among authors: fukumori a. Biochem Biophys Res Commun. 2006 Jun 2;344(2):525-30. doi: 10.1016/j.bbrc.2006.03.173. Epub 2006 Apr 5. Biochem Biophys Res Commun. 2006. PMID: 16630560
Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1.
Tagami S, Okochi M, Yanagida K, Ikuta A, Fukumori A, Matsumoto N, Ishizuka-Katsura Y, Nakayama T, Itoh N, Jiang J, Nishitomi K, Kamino K, Morihara T, Hashimoto R, Tanaka T, Kudo T, Chiba S, Takeda M. Tagami S, et al. Among authors: fukumori a. Mol Cell Biol. 2008 Jan;28(1):165-76. doi: 10.1128/MCB.00863-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967888 Free PMC article.
54 results