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SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer.
Ma HL, Bizet M, Soares Da Costa C, Murisier F, de Bony EJ, Wang MK, Yoshimi A, Lin KT, Riching KM, Wang X, Beckman JI, Arya S, Droin N, Calonne E, Hassabi B, Zhang QY, Li A, Putmans P, Malbec L, Hubert C, Lan J, Mies F, Yang Y, Solary E, Daniels DL, Gupta YK, Deplus R, Abdel-Wahab O, Yang YG, Fuks F. Ma HL, et al. Among authors: fuks f. Mol Cell. 2023 Dec 7;83(23):4239-4254.e10. doi: 10.1016/j.molcel.2023.11.003. Mol Cell. 2023. PMID: 38065062
Atonal homolog 1 is a tumor suppressor gene.
Bossuyt W, Kazanjian A, De Geest N, Van Kelst S, De Hertogh G, Geboes K, Boivin GP, Luciani J, Fuks F, Chuah M, VandenDriessche T, Marynen P, Cools J, Shroyer NF, Hassan BA. Bossuyt W, et al. Among authors: fuks f. PLoS Biol. 2009 Feb 24;7(2):e39. doi: 10.1371/journal.pbio.1000039. PLoS Biol. 2009. PMID: 19243219 Free PMC article.
DNA methyltransferases get connected to chromatin.
Burgers WA, Fuks F, Kouzarides T. Burgers WA, et al. Among authors: fuks f. Trends Genet. 2002 Jun;18(6):275-7. doi: 10.1016/S0168-9525(02)02667-7. Trends Genet. 2002. PMID: 12044346
Viral oncoproteins target the DNA methyltransferases.
Burgers WA, Blanchon L, Pradhan S, de Launoit Y, Kouzarides T, Fuks F. Burgers WA, et al. Among authors: fuks f. Oncogene. 2007 Mar 8;26(11):1650-5. doi: 10.1038/sj.onc.1209950. Epub 2006 Sep 18. Oncogene. 2007. PMID: 16983344 Free PMC article.
98 results