Fukao K - Search Results

1

In Vivo Antiviral Activity of Baloxavir against PA/I38T-Substituted Influenza A Viruses at Clinically Relevant Doses.

Kuroda T, Fukao K, Yoshida S, Oka R, Baba K, Ando Y, Taniguchi K, Noshi T, Shishido T. Kuroda T, et al. Among authors: fukao k. Viruses. 2023 May 11;15(5):1154. doi: 10.3390/v15051154. Viruses. 2023. PMID: 37243240 Free PMC article.

2

Combination treatment with the cap-dependent endonuclease inhibitor baloxavir marboxil and a neuraminidase inhibitor in a mouse model of influenza A virus infection.

Fukao K, Noshi T, Yamamoto A, Kitano M, Ando Y, Noda T, Baba K, Matsumoto K, Higuchi N, Ikeda M, Shishido T, Naito A. Fukao K, et al. J Antimicrob Chemother. 2019 Mar 1;74(3):654-662. doi: 10.1093/jac/dky462. J Antimicrob Chemother. 2019. PMID: 30476172 Free PMC article.

3

Baloxavir marboxil, a novel cap-dependent endonuclease inhibitor potently suppresses influenza virus replication and represents therapeutic effects in both immunocompetent and immunocompromised mouse models.

Fukao K, Ando Y, Noshi T, Kitano M, Noda T, Kawai M, Yoshida R, Sato A, Shishido T, Naito A. Fukao K, et al. PLoS One. 2019 May 20;14(5):e0217307. doi: 10.1371/journal.pone.0217307. eCollection 2019. PLoS One. 2019. PMID: 31107922 Free PMC article.

4

Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model.

Nobori H, Fukao K, Kuroda T, Anan N, Tashima R, Nakashima M, Noda S, Tajiri M, Torii M, Toba S, Uemura K, Sanaki T, Shishido T, Tachibana Y, Kato T. Nobori H, et al. Among authors: fukao k. J Antimicrob Chemother. 2022 Oct 28;77(11):2984-2991. doi: 10.1093/jac/dkac257. J Antimicrob Chemother. 2022. PMID: 35914182 Free PMC article.

5

Baloxavir safety and clinical and virologic outcomes in influenza virus-infected pediatric patients by age group: age-based pooled analysis of two pediatric studies conducted in Japan.

Hirotsu N, Sakaguchi H, Fukao K, Kojima S, Piedra PA, Tsuchiya K, Uehara T. Hirotsu N, et al. Among authors: fukao k. BMC Pediatr. 2023 Jan 21;23(1):35. doi: 10.1186/s12887-023-03841-5. BMC Pediatr. 2023. PMID: 36681802 Free PMC article. Clinical Trial.

6

Efficacy comparison of 3CL protease inhibitors ensitrelvir and nirmatrelvir against SARS-CoV-2 in vitro and in vivo.

Kuroda T, Nobori H, Fukao K, Baba K, Matsumoto K, Yoshida S, Tanaka Y, Watari R, Oka R, Kasai Y, Inoue K, Kawashima S, Shimba A, Hayasaki-Kajiwara Y, Tanimura M, Zhang Q, Tachibana Y, Kato T, Shishido T. Kuroda T, et al. Among authors: fukao k. J Antimicrob Chemother. 2023 Apr 3;78(4):946-952. doi: 10.1093/jac/dkad027. J Antimicrob Chemother. 2023. PMID: 36760083 Free PMC article.

7

Pharmacokinetic and Pharmacodynamic Analysis of the 3CL Protease Inhibitor Ensitrelvir in a SARS-CoV-2 Infection Mouse Model.

Fukao K, Nobori H, Kuroda T, Baba K, Matsumoto K, Tanaka Y, Tachibana Y, Kato T, Shishido T. Fukao K, et al. Viruses. 2023 Oct 5;15(10):2052. doi: 10.3390/v15102052. Viruses. 2023. PMID: 37896829 Free PMC article.

8

Prophylactic Treatment with Baloxavir Protects Mice from Lethal Infection with Influenza A and B Viruses.

Fukao K, Noshi T, Shano S, Baba K, Sato K, Sakuramoto M, Kitade N, Tanioka H, Kusakabe S, Shishido T. Fukao K, et al. Viruses. 2023 Nov 16;15(11):2264. doi: 10.3390/v15112264. Viruses. 2023. PMID: 38005940 Free PMC article.

9

Prophylactic effect of ensitrelvir in mice infected with SARS-CoV-2.

Nobori H, Baba K, Kuroda T, Baba K, Matsumoto K, Yoshida S, Watari R, Tachibana Y, Kato T, Fukao K. Nobori H, et al. Among authors: fukao k. Antiviral Res. 2024 Apr;224:105852. doi: 10.1016/j.antiviral.2024.105852. Epub 2024 Feb 28. Antiviral Res. 2024. PMID: 38428748 Free article.

10

Discovery and structure-activity relationship study of 2-piperazinyl-benzothiazole derivatives as potent and selective PPARδ agonists.

Kato T, Ohara T, Suzuki N, Naya N, Fukao K, Tokuyama R, Muto S, Fukasawa H, Itai A, Matsumura KI. Kato T, et al. Among authors: fukao k. Bioorg Med Chem. 2023 Mar 15;82:117215. doi: 10.1016/j.bmc.2023.117215. Epub 2023 Feb 17. Bioorg Med Chem. 2023. PMID: 36840990

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