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GTN057, a komaroviquinone derivative, induced myeloma cells' death in vivo and inhibited c-MET tyrosine kinase.
Okayama M, Fujimori K, Sato M, Samata K, Kurita K, Sugiyama H, Suto Y, Iwasaki G, Yamada T, Kiuchi F, Ichikawa D, Matsushita M, Hirao M, Kunieda H, Yamazaki K, Hattori Y. Okayama M, et al. Among authors: fujimori k. Cancer Med. 2023 Apr;12(8):9749-9759. doi: 10.1002/cam4.5691. Epub 2023 Feb 24. Cancer Med. 2023. PMID: 36825580 Free PMC article.
A novel derivative (GTN024) from a natural product, komaroviquinone, induced the apoptosis of high-risk myeloma cells via reactive oxygen production and ER stress.
Okayama M, Kitabatake S, Sato M, Fujimori K, Ichikawa D, Matsushita M, Suto Y, Iwasaki G, Yamada T, Kiuchi F, Hirao M, Kunieda H, Osada M, Okamoto S, Hattori Y. Okayama M, et al. Among authors: fujimori k. Biochem Biophys Res Commun. 2018 Nov 2;505(3):787-793. doi: 10.1016/j.bbrc.2018.09.177. Epub 2018 Oct 5. Biochem Biophys Res Commun. 2018. PMID: 30297108
Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma.
Suto Y, Sato M, Fujimori K, Kitabatake S, Okayama M, Ichikawa D, Matsushita M, Yamagiwa N, Iwasaki G, Kiuchi F, Hattori Y. Suto Y, et al. Among authors: fujimori k. Bioorg Med Chem Lett. 2017 Oct 1;27(19):4558-4563. doi: 10.1016/j.bmcl.2017.08.054. Epub 2017 Aug 30. Bioorg Med Chem Lett. 2017. PMID: 28882484
Risk of gestational diabetes in women with PCOS based on body mass index: The Japan Environment and Children's Study.
Okoshi C, Kyozuka H, Fukuda T, Yasuda S, Murata T, Isogami H, Sato A, Ogata Y, Hosoya M, Yasumura S, Hashimoto K, Nishigori H, Kamijima M, Yamazaki S, Ohya Y, Kishi R, Yaegashi N, Mori C, Ito S, Yamagata Z, Inadera H, Nakayama T, Sobue T, Shima M, Kageyama S, Suganuma N, Ohga S, Katoh T, Fujimori K, Takahashi T. Okoshi C, et al. Among authors: fujimori k. J Clin Endocrinol Metab. 2024 May 4:dgae293. doi: 10.1210/clinem/dgae293. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38703083
Early-onset dementia and risk of hip fracture and major osteoporotic fractures.
Matsumoto S, Hosoi T, Yakabe M, Fujimori K, Tamaki J, Nakatoh S, Ishii S, Okimoto N, Akishita M, Iki M, Ogawa S. Matsumoto S, et al. Among authors: fujimori k. Alzheimers Dement. 2024 May;20(5):3388-3396. doi: 10.1002/alz.13815. Epub 2024 Apr 1. Alzheimers Dement. 2024. PMID: 38561022
Prevalence and causes of chronic cough in Japan.
Ishiura Y, Fujimura M, Ogawa H, Hara J, Shintani H, Hozawa S, Atsuta R, Fukumitsu K, Inoue H, Shioya T, Muraki M, Amemiya T, Ohkura N, Oribe Y, Tanaka H, Yamada T, Toyoshima M, Fujimori K, Ishizuka T, Kagaya M, Suzuki T, Kita T, Nishi K, Ueda A, Miyata Y, Kitada J, Yamamura K, Abo M, Takeda N, Shirai T, Tajiri T, Yoshihara S, Akamatsu T, Sawaguchi H, Nagano T, Hanada S, Masuda S, Ohmichi M, Ito T, Sagara H, Matsumoto H, Niimi A; Japan Cough Society. Ishiura Y, et al. Among authors: fujimori k. Respir Investig. 2024 May;62(3):442-448. doi: 10.1016/j.resinv.2024.02.017. Epub 2024 Mar 23. Respir Investig. 2024. PMID: 38522360 Free article.
955 results