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Destabilization of mitochondrial functions as a target against breast cancer progression: Role of TPP(+)-linked-polyhydroxybenzoates.
Sandoval-Acuña C, Fuentes-Retamal S, Guzmán-Rivera D, Peredo-Silva L, Madrid-Rojas M, Rebolledo S, Castro-Castillo V, Pavani M, Catalán M, Maya JD, Jara JA, Parra E, Calaf GM, Speisky H, Ferreira J. Sandoval-Acuña C, et al. Toxicol Appl Pharmacol. 2016 Oct 15;309:2-14. doi: 10.1016/j.taap.2016.08.018. Epub 2016 Aug 20. Toxicol Appl Pharmacol. 2016. PMID: 27554043
Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells.
Fuentes-Retamal S, Sandoval-Acuña C, Peredo-Silva L, Guzmán-Rivera D, Pavani M, Torrealba N, Truksa J, Castro-Castillo V, Catalán M, Kemmerling U, Urra FA, Ferreira J. Fuentes-Retamal S, et al. Cells. 2020 Feb 11;9(2):407. doi: 10.3390/cells9020407. Cells. 2020. PMID: 32053908 Free PMC article.
Simvastatin Improves Cardiac Function through Notch 1 Activation in BALB/c Mice with Chronic Chagas Cardiomyopathy.
Guzmán-Rivera D, Liempi A, González-Herrera F, Fuentes-Retamal S, Carrillo I, Abarca P, Castillo C, Kemmerling U, Pesce B, Maya JD. Guzmán-Rivera D, et al. Among authors: fuentes retamal s. Antimicrob Agents Chemother. 2020 Jul 22;64(8):e02141-19. doi: 10.1128/AAC.02141-19. Print 2020 Jul 22. Antimicrob Agents Chemother. 2020. PMID: 32393497 Free PMC article.
FRI-1 Is an Anti-Cancer Isoquinolinequinone That Inhibits the Mitochondrial Bioenergetics and Blocks Metabolic Shifts by Redox Disruption in Breast Cancer Cells.
Córdova-Delgado M, Fuentes-Retamal S, Palominos C, López-Torres C, Guzmán-Rivera D, Ramírez-Rodríguez O, Araya-Maturana R, Urra FA. Córdova-Delgado M, et al. Among authors: fuentes retamal s. Antioxidants (Basel). 2021 Oct 14;10(10):1618. doi: 10.3390/antiox10101618. Antioxidants (Basel). 2021. PMID: 34679752 Free PMC article.
Aspirin-triggered resolvin D1 reduces parasitic cardiac load by decreasing inflammation in a murine model of early chronic Chagas disease.
Carrillo I, Rabelo RAN, Barbosa C, Rates M, Fuentes-Retamal S, González-Herrera F, Guzmán-Rivera D, Quintero H, Kemmerling U, Castillo C, Machado FS, Díaz-Araya G, Maya JD. Carrillo I, et al. Among authors: fuentes retamal s. PLoS Negl Trop Dis. 2021 Nov 16;15(11):e0009978. doi: 10.1371/journal.pntd.0009978. eCollection 2021 Nov. PLoS Negl Trop Dis. 2021. PMID: 34784372 Free PMC article.
An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells.
Donoso-Bustamante V, Borrego EA, Schiaffino-Bustamante Y, Gutiérrez DA, Millas-Vargas JP, Fuentes-Retamal S, Correa P, Carrillo I, Aguilera RJ, Miranda D, Chávez-Báez I, Pulgar R, Urra FA, Varela-Ramírez A, Araya-Maturana R. Donoso-Bustamante V, et al. Among authors: fuentes retamal s. Bioorg Chem. 2020 Jul;100:103935. doi: 10.1016/j.bioorg.2020.103935. Epub 2020 May 18. Bioorg Chem. 2020. PMID: 32454391
A paraguayan toad Rhinella schneideri preparation based on Mbya tradition increases mitochondrial bioenergetics with migrastatic effects dependent on AMPK in breast cancer cells.
Schmeda-Hirschmann G, Burgos-Edwards A, Rojas de Arias A, López-Torres C, Palominos C, Fuentes-Retamal S, Herrera Y, Dubois-Camacho K, Urra FA. Schmeda-Hirschmann G, et al. Among authors: fuentes retamal s. J Ethnopharmacol. 2022 Aug 10;294:115344. doi: 10.1016/j.jep.2022.115344. Epub 2022 May 6. J Ethnopharmacol. 2022. PMID: 35526731
14 results