Fu W - Search Results

1

7β-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues.

Sun HJ, Wang YH, Yuan CM, Kong LH, Xu XJ, Wang YJ, Wu HH, Lin C, Qian YY, Huang HM, Xiao L, Liu X, He Q, Fang SY, Xue DQ, Yang XC, Chen H, Zheng YL, Zheng L, Yu LQ, Xie Q, Fu W, Li W, Liu JG, Qiu ZB, Shao LM. Sun HJ, et al. Among authors: fu w. Bioorg Med Chem. 2018 Aug 7;26(14):4254-4263. doi: 10.1016/j.bmc.2018.07.020. Epub 2018 Jul 24. Bioorg Med Chem. 2018. PMID: 30054192

2

3-Arylamino-2H-1,2,4-benzothiadiazin-5-ol 1,1-dioxides as novel and selective CXCR2 antagonists.

Wang Y, Busch-Petersen J, Wang F, Ma L, Fu W, Kerns JK, Jin J, Palovich MR, Shen JK, Burman M, Foley JJ, Schmidt DB, Hunsberger GE, Sarau HM, Widdowson KL. Wang Y, et al. Among authors: fu w. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3864-7. doi: 10.1016/j.bmcl.2007.05.011. Epub 2007 May 10. Bioorg Med Chem Lett. 2007. PMID: 17524641

3

Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation.

Xie Q, Wang H, Xia Z, Lu M, Zhang W, Wang X, Fu W, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu Z, Chen H. Xie Q, et al. Among authors: fu w. J Med Chem. 2008 Apr 10;51(7):2027-36. doi: 10.1021/jm070154q. Epub 2008 Mar 12. J Med Chem. 2008. PMID: 18333606

4

Muscarinic acetylcholine receptor antagonists: SAR and optimization of tyrosine ureas.

Jin J, Wang Y, Shi D, Wang F, Fu W, Davis RS, Jin Q, Foley JJ, Sarau HM, Morrow DM, Moore ML, Rivero RA, Palovich M, Salmon M, Belmonte KE, Busch-Petersen J. Jin J, et al. Among authors: fu w. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5481-6. doi: 10.1016/j.bmcl.2008.09.020. Epub 2008 Sep 10. Bioorg Med Chem Lett. 2008. PMID: 18818072

5

The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative reveals disruption of the catalytic triad.

Paz A, Xie Q, Greenblatt HM, Fu W, Tang Y, Silman I, Qiu Z, Sussman JL. Paz A, et al. Among authors: fu w. J Med Chem. 2009 Apr 23;52(8):2543-9. doi: 10.1021/jm801657v. J Med Chem. 2009. PMID: 19326912

6

Highly selective and potent mu opioid ligands by unexpected substituent on morphine skeleton.

Li W, Tao YM, Tang Y, Xu XJ, Chen J, Fu W, Wang XH, Chao B, Sheng W, Xie Q, Qiu ZB, Liu JG. Li W, et al. Among authors: fu w. Bioorg Med Chem Lett. 2010 Jan 1;20(1):418-21. doi: 10.1016/j.bmcl.2009.07.119. Epub 2009 Jul 29. Bioorg Med Chem Lett. 2010. PMID: 19932964

7

Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.

Ma K, Wang P, Fu W, Wan X, Zhou L, Chu Y, Ye D. Ma K, et al. Among authors: fu w. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6724-7. doi: 10.1016/j.bmcl.2011.09.054. Epub 2011 Sep 20. Bioorg Med Chem Lett. 2011. PMID: 21996518

8

Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives.

Fu W, Wang J, Yu L, Zhao L, Lu N, You Q, Guo Q, Li Z. Fu W, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1118-21. doi: 10.1016/j.bmcl.2011.11.117. Epub 2011 Dec 6. Bioorg Med Chem Lett. 2012. PMID: 22196122

9

Molecular insights into the D1R agonist and D2R/D3R antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations.

Li B, Li W, Du P, Yu KQ, Fu W. Li B, et al. Among authors: fu w. J Phys Chem B. 2012 Jul 19;116(28):8121-30. doi: 10.1021/jp3049235. Epub 2012 Jul 3. J Phys Chem B. 2012. PMID: 22702398

10

Design, synthesis, and biological evaluation of deuterated C-aryl glycoside as a potent and long-acting renal sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes.

Xu G, Lv B, Roberge JY, Xu B, Du J, Dong J, Chen Y, Peng K, Zhang L, Tang X, Feng Y, Xu M, Fu W, Zhang W, Zhu L, Deng Z, Sheng Z, Welihinda A, Sun X. Xu G, et al. Among authors: fu w. J Med Chem. 2014 Feb 27;57(4):1236-51. doi: 10.1021/jm401780b. Epub 2014 Feb 12. J Med Chem. 2014. PMID: 24456245

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