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PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y. Li Y, et al. Among authors: fu tm. Nat Struct Mol Biol. 2024 Mar;31(3):413-423. doi: 10.1038/s41594-023-01172-8. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177683
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Robert Hollingsworth L, David L, Li Y, Griswold AR, Ruan J, Sharif H, Fontana P, Orth-He EL, Fu TM, Bachovchin DA, Wu H. Robert Hollingsworth L, et al. Among authors: fu tm. Nat Commun. 2021 Jan 8;12(1):189. doi: 10.1038/s41467-020-20320-y. Nat Commun. 2021. PMID: 33420033 Free PMC article.
Molecular basis of Gabija anti-phage supramolecular assemblies.
Yang XY, Shen Z, Xie J, Greenwald J, Marathe I, Lin Q, Xie WJ, Wysocki VH, Fu TM. Yang XY, et al. Among authors: fu tm. Nat Struct Mol Biol. 2024 Apr 16. doi: 10.1038/s41594-024-01283-w. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38627580
Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Xia S, et al. Among authors: fu tm. Nature. 2021 May;593(7860):607-611. doi: 10.1038/s41586-021-03478-3. Epub 2021 Apr 21. Nature. 2021. PMID: 33883744 Free PMC article.
Glutamine synthetase licenses APC/C-mediated mitotic progression to drive cell growth.
Zhao JS, Shi S, Qu HY, Keckesova Z, Cao ZJ, Yang LX, Yu X, Feng L, Shi Z, Krakowiak J, Mao RY, Shen YT, Fan YM, Fu TM, Ye C, Xu D, Gao X, You J, Li W, Liang T, Lu Z, Feng YX. Zhao JS, et al. Among authors: fu tm. Nat Metab. 2022 Feb;4(2):239-253. doi: 10.1038/s42255-021-00524-2. Epub 2022 Feb 10. Nat Metab. 2022. PMID: 35145325
214 results