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Estradiol contributes to sex differences in resilience to septic-induced metabolic dysregulation and dysfunction in the heart via GPER-1-mediated PPARδ/NLRP3 signaling.
Adu-Amankwaah J, Adekunle AO, Tang Z, Bushi A, Tan R, Fu L, Gong Z, Ma Z, Mprah R, Noah MLN, Wowui PI, Ong'achwa Machuki J, Pan X, TaoLi, Sun H. Adu-Amankwaah J, et al. Among authors: fu l. Metabolism. 2024 May 16:155934. doi: 10.1016/j.metabol.2024.155934. Online ahead of print. Metabolism. 2024. PMID: 38762141
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model.
Braun MG, Ashkenazi A, Beveridge RE, Castanedo G, Wallweber HA, Beresini MH, Clark KR, De Bruyn T, Fu L, Gibbons P, Jiang F, Kaufman S, Kan D, Kiefer JR, Leclerc JP, Lemire A, Ly C, Segal E, Sims J, Wang W, Wei W, Zhao L, Schwarz JB, Rudolph J. Braun MG, et al. Among authors: fu l. J Med Chem. 2024 May 15. doi: 10.1021/acs.jmedchem.3c02425. Online ahead of print. J Med Chem. 2024. PMID: 38748820
8,067 results