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SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.
Xue Y, Morris JL, Yang K, Fu Z, Zhu X, Johnson F, Meehan B, Witkowski L, Yasmeen A, Golenar T, Coatham M, Morin G, Monast A, Pilon V, Fiset PO, Jung S, Gonzalez AV, Camilleri-Broet S, Fu L, Postovit LM, Spicer J, Gotlieb WH, Guiot MC, Rak J, Park M, Lockwood W, Foulkes WD, Prudent J, Huang S. Xue Y, et al. Among authors: fu z, fu l. Nat Commun. 2021 Sep 13;12(1):5404. doi: 10.1038/s41467-021-25260-9. Nat Commun. 2021. PMID: 34518526 Free PMC article.
Molecular characterization of DICER1-mutated pituitary blastoma.
Nadaf J, de Kock L, Chong AS, Korbonits M, Thorner P, Benlimame N, Fu L, Peet A, Warner J, Ploner O, Shuangshoti S, Albrecht S, Hamel N, Priest JR, Rivera B, Ragoussis J, Foulkes WD. Nadaf J, et al. Among authors: fu l. Acta Neuropathol. 2021 Jun;141(6):929-944. doi: 10.1007/s00401-021-02283-6. Epub 2021 Mar 1. Acta Neuropathol. 2021. PMID: 33644822
Long-term tumour dormancy in a BRCA1 heterozygote.
Amuzu S, Fu L, Demko N, Rivera B, Domecq C, de Kock L, Hamel N, Gilbert L, Polak P, Ragoussis J, Foulkes WD. Amuzu S, et al. Among authors: fu l. J Med Genet. 2023 Jan;60(1):33-35. doi: 10.1136/jmedgenet-2021-108269. Epub 2022 Jan 17. J Med Genet. 2023. PMID: 35039446 No abstract available.
PRAME protein expression in DICER1-related tumours.
Thorner PS, Chong AS, Nadaf J, Benlimame N, Marrano P, Chami R, Fu L, Foulkes WD. Thorner PS, et al. Among authors: fu l. J Pathol Clin Res. 2022 May;8(3):294-304. doi: 10.1002/cjp2.264. Epub 2022 Mar 16. J Pathol Clin Res. 2022. PMID: 35297207 Free PMC article.
PRAME protein expression in DICER1-related tumours.
Thorner PS, Chong AS, Nadaf J, Benlimame N, Marrano P, Chami R, Fu L, Foulkes WD. Thorner PS, et al. Among authors: fu l. J Pathol Clin Res. 2022 Nov;8(6):579-581. doi: 10.1002/cjp2.293. Epub 2022 Aug 20. J Pathol Clin Res. 2022. PMID: 35986592 Free PMC article. No abstract available.
Author Correction: SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.
Xue Y, Morris JL, Yang K, Fu Z, Zhu X, Johnson F, Meehan B, Witkowski L, Yasmeen A, Golenar T, Coatham M, Morin G, Monast A, Pilon V, Fiset PO, Jung S, Gonzalez AV, Camilleri-Broet S, Fu L, Postovit LM, Spicer J, Gotlieb WH, Guiot MC, Rak J, Park M, Lockwood W, Foulkes WD, Prudent J, Huang S. Xue Y, et al. Among authors: fu z, fu l. Nat Commun. 2023 Mar 21;14(1):1552. doi: 10.1038/s41467-023-37144-1. Nat Commun. 2023. PMID: 36944611 Free PMC article. No abstract available.
Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss.
Zhu X, Fu Z, Chen SY, Ong D, Aceto G, Ho R, Steinberger J, Monast A, Pilon V, Li E, Ta M, Ching K, Adams BN, Negri GL, Choiniere L, Fu L, Pavlakis K, Pirrotte P, Avizonis DZ, Trent J, Weissman BE, Klein Geltink RI, Morin GB, Park M, Huntsman DG, Foulkes WD, Wang Y, Huang S. Zhu X, et al. Among authors: fu z, fu l. Nat Commun. 2023 May 20;14(1):2894. doi: 10.1038/s41467-023-38594-3. Nat Commun. 2023. PMID: 37210563 Free PMC article.
Segregation, immunohistochemical, molecular and functional analyses classify a novel missense variant in fumarate hydratase (FH) as pathogenic.
Ouchene L, Wilde B, Chan-Pak-Choon F, Camacho Valenzuela J, Brimo F, Witkowski L, Christofk H, Domecq C, Fu L, Weber E, Lemieux Anglin B, Netchiporouk E, Foulkes WD. Ouchene L, et al. Among authors: fu l. Genes Chromosomes Cancer. 2024 Feb;63(2):e23221. doi: 10.1002/gcc.23221. Genes Chromosomes Cancer. 2024. PMID: 38682608
8,034 results