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Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice.
Zhuang GZ, Upadhyay U, Tong X, Kang Y, Erasso DM, Fu ES, Sarantopoulos KD, Martin ER, Wiltshire T, Diatchenko L, Smith SB, Maixner W, Levitt RC. Zhuang GZ, et al. Among authors: fu es. Gene Ther. 2018 Jul;25(4):297-311. doi: 10.1038/s41434-018-0018-7. Epub 2018 Apr 24. Gene Ther. 2018. PMID: 29789638 Free PMC article.
Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.
Zhuang GZ, Keeler B, Grant J, Bianchi L, Fu ES, Zhang YP, Erasso DM, Cui JG, Wiltshire T, Li Q, Hao S, Sarantopoulos KD, Candiotti K, Wishnek SM, Smith SB, Maixner W, Diatchenko L, Martin ER, Levitt RC. Zhuang GZ, et al. Among authors: fu es. PLoS One. 2015 Mar 3;10(3):e0118273. doi: 10.1371/journal.pone.0118273. eCollection 2015. PLoS One. 2015. PMID: 25734498 Free PMC article.
29 results