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CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice.
Wang CH, Lundh M, Fu A, Kriszt R, Huang TL, Lynes MD, Leiria LO, Shamsi F, Darcy J, Greenwood BP, Narain NR, Tolstikov V, Smith KL, Emanuelli B, Chang YT, Hagen S, Danial NN, Kiebish MA, Tseng YH. Wang CH, et al. Among authors: fu a. Sci Transl Med. 2020 Aug 26;12(558):eaaz8664. doi: 10.1126/scitranslmed.aaz8664. Sci Transl Med. 2020. PMID: 32848096 Free PMC article.
Grasping for aspartate in tumour metabolism.
Fu A, Danial NN. Fu A, et al. Nat Cell Biol. 2018 Jul;20(7):738-739. doi: 10.1038/s41556-018-0137-9. Nat Cell Biol. 2018. PMID: 29941932 No abstract available.
UCP1 governs liver extracellular succinate and inflammatory pathogenesis.
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Garrity R, Tran NV, Bradshaw GA, Fu A, Szpyt J, Reddy A, Prendeville H, Danial NN, Gygi SP, Lynch L, Chouchani ET. Mills EL, et al. Among authors: fu a. Nat Metab. 2021 May;3(5):604-617. doi: 10.1038/s42255-021-00389-5. Epub 2021 May 17. Nat Metab. 2021. PMID: 34002097 Free PMC article. Review.
Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor.
Bird GH, Fu A, Escudero S, Godes M, Opoku-Nsiah K, Wales TE, Cameron MD, Engen JR, Danial NN, Walensky LD. Bird GH, et al. Among authors: fu a. ACS Chem Biol. 2020 Jun 19;15(6):1340-1348. doi: 10.1021/acschembio.0c00308. Epub 2020 May 27. ACS Chem Biol. 2020. PMID: 32348108 Free PMC article.
Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation.
Fu A, Alvarez-Perez JC, Avizonis D, Kin T, Ficarro SB, Choi DW, Karakose E, Badur MG, Evans L, Rosselot C, Bridon G, Bird GH, Seo HS, Dhe-Paganon S, Kamphorst JJ, Stewart AF, James Shapiro AM, Marto JA, Walensky LD, Jones RG, Garcia-Ocana A, Danial NN. Fu A, et al. Nat Metab. 2020 May;2(5):432-446. doi: 10.1038/s42255-020-0199-4. Epub 2020 May 11. Nat Metab. 2020. PMID: 32694660 Free PMC article.
LKB1 couples glucose metabolism to insulin secretion in mice.
Fu A, Robitaille K, Faubert B, Reeks C, Dai XQ, Hardy AB, Sankar KS, Ogrel S, Al-Dirbashi OY, Rocheleau JV, Wheeler MB, MacDonald PE, Jones R, Screaton RA. Fu A, et al. Diabetologia. 2015 Jul;58(7):1513-22. doi: 10.1007/s00125-015-3579-7. Epub 2015 Apr 16. Diabetologia. 2015. PMID: 25874445
1,190 results