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Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action.
Kazakova A, Frydrych I, Jakubcová N, Pokorný J, Lišková B, Gurská S, Džubák P, Hajdúch M, Urban M. Kazakova A, et al. Among authors: frydrych i. Eur J Med Chem. 2024 Apr 5;269:116336. doi: 10.1016/j.ejmech.2024.116336. Epub 2024 Mar 18. Eur J Med Chem. 2024. PMID: 38520761 Free article.
Basic Methods of Cell Cycle Analysis.
Ligasová A, Frydrych I, Koberna K. Ligasová A, et al. Among authors: frydrych i. Int J Mol Sci. 2023 Feb 12;24(4):3674. doi: 10.3390/ijms24043674. Int J Mol Sci. 2023. PMID: 36835083 Free PMC article. Review.
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes.
Borková L, Frydrych I, Vránová B, Jakubcová N, Lišková B, Gurská S, Džubák P, Pavliš P, Hajdúch M, Urban M. Borková L, et al. Among authors: frydrych i. Eur J Med Chem. 2022 Dec 15;244:114850. doi: 10.1016/j.ejmech.2022.114850. Epub 2022 Oct 20. Eur J Med Chem. 2022. PMID: 36283179
Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs.
Hodoň J, Frydrych I, Trhlíková Z, Pokorný J, Borková L, Benická S, Vlk M, Lišková B, Kubíčková A, Medvedíková M, Pisár M, Šarek J, Das V, Ligasová A, Koberna K, Džubák P, Hajdúch M, Urban M. Hodoň J, et al. Among authors: frydrych i. Eur J Med Chem. 2022 Dec 5;243:114777. doi: 10.1016/j.ejmech.2022.114777. Epub 2022 Sep 23. Eur J Med Chem. 2022. PMID: 36174412 Free article.
28 results