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A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway.
Elsasser S, Elia LP, Morimoto RI, Powers ET, Finley D, Costa B, Budron M, Tokuno Z, Wang S, Iyer RG, Barth B, Mockler E, Finkbeiner S, Gestwicki JE, Richardson RAK, Stoeger T, Tan EP, Xiao Q, Cole CM, Massey LA, Garza D, Kelly JW, Rainbolt TK, Chou CC, Masto VB, Frydman J, Nixon RA. Elsasser S, et al. Among authors: frydman j. bioRxiv [Preprint]. 2023 Mar 24:2023.03.22.533675. doi: 10.1101/2023.03.22.533675. bioRxiv. 2023. PMID: 36993380 Free PMC article. Preprint.
Dynamics and clustering of IRE1α during ER stress.
Rainbolt TK, Frydman J. Rainbolt TK, et al. Among authors: frydman j. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3352-3354. doi: 10.1073/pnas.1921799117. Epub 2020 Feb 4. Proc Natl Acad Sci U S A. 2020. PMID: 32019880 Free PMC article. No abstract available.
A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities.
Shao H, Taguwa S, Gilbert L, Shkedi A, Sannino S, Guerriero CJ, Gale-Day ZJ, Young ZT, Brodsky JL, Weissman J, Gestwicki JE, Frydman J. Shao H, et al. Among authors: frydman j. Cell Chem Biol. 2022 Aug 18;29(8):1303-1316.e3. doi: 10.1016/j.chembiol.2022.06.006. Epub 2022 Jul 12. Cell Chem Biol. 2022. PMID: 35830852 Free PMC article.
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: frydman j. bioRxiv [Preprint]. 2023 Mar 27:2023.03.27.534444. doi: 10.1101/2023.03.27.534444. bioRxiv. 2023. PMID: 37034684 Free PMC article. Preprint.
206 results