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Novel indolylarylsulfone derivatives as covalent HIV-1 reverse transcriptase inhibitors specifically targeting the drug-resistant mutant Y181C.
Gao P, Song S, Frutos-Beltrán E, Li W, Sun B, Kang D, Zou J, Zhang J, Pannecouque C, De Clercq E, Menéndez-Arias L, Zhan P, Liu X. Gao P, et al. Among authors: frutos beltran e. Bioorg Med Chem. 2021 Jan 15;30:115927. doi: 10.1016/j.bmc.2020.115927. Epub 2020 Dec 10. Bioorg Med Chem. 2021. PMID: 33352387 Free article.
Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors.
Kang D, Urhan Ç, Wei F, Frutos-Beltrán E, Sun L, Álvarez M, Feng D, Tao Y, Pannecouque C, De Clercq E, Menéndez-Arias L, Liu X, Zhan P. Kang D, et al. Among authors: frutos beltran e. Eur J Med Chem. 2021 Dec 5;225:113769. doi: 10.1016/j.ejmech.2021.113769. Epub 2021 Aug 11. Eur J Med Chem. 2021. PMID: 34403976 Free article.
Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors.
Zhang L, Wei F, Borrego D, Zhao F, Río JMD, Frutos-Beltrán E, Zhang J, Xu S, López-Carrobles N, Gao S, Kang D, Pannecouque C, Clercq E, Liu X, Menéndez-Arias L, Zhan P. Zhang L, et al. Among authors: frutos beltran e. Eur J Med Chem. 2022 Oct 5;240:114563. doi: 10.1016/j.ejmech.2022.114563. Epub 2022 Jun 26. Eur J Med Chem. 2022. PMID: 35780636
An Update on Antiretroviral Therapy.
Menéndez-Arias L, Martín-Alonso S, Frutos-Beltrán E. Menéndez-Arias L, et al. Among authors: frutos beltran e. Adv Exp Med Biol. 2021;1322:31-61. doi: 10.1007/978-981-16-0267-2_2. Adv Exp Med Biol. 2021. PMID: 34258736
Reverse Transcriptase: From Transcriptomics to Genome Editing.
Martín-Alonso S, Frutos-Beltrán E, Menéndez-Arias L. Martín-Alonso S, et al. Among authors: frutos beltran e. Trends Biotechnol. 2021 Feb;39(2):194-210. doi: 10.1016/j.tibtech.2020.06.008. Epub 2020 Jul 8. Trends Biotechnol. 2021. PMID: 32653101 Review.