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Page 1
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.
Bello C, Dal Bello G, Cea M, Nahimana A, Aubry D, Garuti A, Motta G, Moran E, Fruscione F, Pronzato P, Grossi F, Patrone F, Ballestrero A, Dupuis M, Sordat B, Zimmermann K, Loretan J, Wartmann M, Duchosal MA, Nencioni A, Vogel P. Bello C, et al. Among authors: fruscione f. Bioorg Med Chem. 2011 Dec 15;19(24):7720-7. doi: 10.1016/j.bmc.2011.07.053. Epub 2011 Jul 30. Bioorg Med Chem. 2011. PMID: 22079865
Novel 2-[(benzylamino)methyl]pyrrolidine-3,4-diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies.
Bello C, Cea M, Dal Bello G, Garuti A, Rocco I, Cirmena G, Moran E, Nahimana A, Duchosal MA, Fruscione F, Pronzato P, Grossi F, Patrone F, Ballestrero A, Dupuis M, Sordat B, Nencioni A, Vogel P. Bello C, et al. Among authors: fruscione f. Bioorg Med Chem. 2010 May 1;18(9):3320-34. doi: 10.1016/j.bmc.2010.03.009. Epub 2010 Mar 9. Bioorg Med Chem. 2010. PMID: 20346684
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells.
Zoppoli G, Cea M, Soncini D, Fruscione F, Rudner J, Moran E, Caffa I, Bedognetti D, Motta G, Ghio R, Ferrando F, Ballestrero A, Parodi S, Belka C, Patrone F, Bruzzone S, Nencioni A. Zoppoli G, et al. Among authors: fruscione f. Exp Hematol. 2010 Nov;38(11):979-88. doi: 10.1016/j.exphem.2010.07.013. Epub 2010 Aug 7. Exp Hematol. 2010. PMID: 20696207 Free article.
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
Bruzzone S, Fruscione F, Morando S, Ferrando T, Poggi A, Garuti A, D'Urso A, Selmo M, Benvenuto F, Cea M, Zoppoli G, Moran E, Soncini D, Ballestrero A, Sordat B, Patrone F, Mostoslavsky R, Uccelli A, Nencioni A. Bruzzone S, et al. Among authors: fruscione f. PLoS One. 2009 Nov 19;4(11):e7897. doi: 10.1371/journal.pone.0007897. PLoS One. 2009. PMID: 19936064 Free PMC article.
APO866 activity in hematologic malignancies: a preclinical in vitro study.
Cea M, Zoppoli G, Bruzzone S, Fruscione F, Moran E, Garuti A, Rocco I, Cirmena G, Casciaro S, Olcese F, Pierri I, Cagnetta A, Ferrando F, Ghio R, Gobbi M, Ballestrero A, Patrone F, Nencioni A. Cea M, et al. Among authors: fruscione f. Blood. 2009 Jun 4;113(23):6035-7; author reply 6037-8. doi: 10.1182/blood-2009-03-209213. Blood. 2009. PMID: 19498032 Free article. No abstract available.
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells.
Cea M, Soncini D, Fruscione F, Raffaghello L, Garuti A, Emionite L, Moran E, Magnone M, Zoppoli G, Reverberi D, Caffa I, Salis A, Cagnetta A, Bergamaschi M, Casciaro S, Pierri I, Damonte G, Ansaldi F, Gobbi M, Pistoia V, Ballestrero A, Patrone F, Bruzzone S, Nencioni A. Cea M, et al. Among authors: fruscione f. PLoS One. 2011;6(7):e22739. doi: 10.1371/journal.pone.0022739. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818379 Free PMC article.
51 results