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Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators.
Vu-Dac N, Gervois P, Jakel H, Nowak M, Bauge E, Dehondt H, Staels B, Pennacchio LA, Rubin EM, Fruchart-Najib J, Fruchart JC. Vu-Dac N, et al. Among authors: fruchart najib j, fruchart jc. J Biol Chem. 2003 May 16;278(20):17982-5. doi: 10.1074/jbc.M212191200. Epub 2003 Mar 12. J Biol Chem. 2003. PMID: 12637506 Free article.
Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5.
Fruchart-Najib J, Baugé E, Niculescu LS, Pham T, Thomas B, Rommens C, Majd Z, Brewer B, Pennacchio LA, Fruchart JC. Fruchart-Najib J, et al. Among authors: fruchart jc. Biochem Biophys Res Commun. 2004 Jun 25;319(2):397-404. doi: 10.1016/j.bbrc.2004.05.003. Biochem Biophys Res Commun. 2004. PMID: 15178420
Transcriptional regulation of apolipoprotein A5 gene expression by the nuclear receptor RORalpha.
Genoux A, Dehondt H, Helleboid-Chapman A, Duhem C, Hum DW, Martin G, Pennacchio LA, Staels B, Fruchart-Najib J, Fruchart JC. Genoux A, et al. Among authors: fruchart najib j, fruchart jc. Arterioscler Thromb Vasc Biol. 2005 Jun;25(6):1186-92. doi: 10.1161/01.ATV.0000163841.85333.83. Epub 2005 Mar 24. Arterioscler Thromb Vasc Biol. 2005. PMID: 15790933
The RXR agonist bexarotene improves cholesterol homeostasis and inhibits atherosclerosis progression in a mouse model of mixed dyslipidemia.
Lalloyer F, Fiévet C, Lestavel S, Torpier G, van der Veen J, Touche V, Bultel S, Yous S, Kuipers F, Paumelle R, Fruchart JC, Staels B, Tailleux A. Lalloyer F, et al. Among authors: fruchart jc. Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2731-7. doi: 10.1161/01.ATV.0000248101.93488.84. Epub 2006 Sep 28. Arterioscler Thromb Vasc Biol. 2006. PMID: 17008586
Pleiotropic effects of fibrates.
Chinetti-Gbaguidi G, Fruchart JC, Staels B. Chinetti-Gbaguidi G, et al. Among authors: fruchart jc. Curr Atheroscler Rep. 2005 Sep;7(5):396-401. doi: 10.1007/s11883-005-0053-x. Curr Atheroscler Rep. 2005. PMID: 16105484 Review.
708 results