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The QP509L and Q706L superfamily II RNA helicases of African swine fever virus are required for viral replication, having non-redundant activities.
Emerg Microbes Infect. 2019;8(1):291-302. doi: 10.1080/22221751.2019.1578624.
Emerg Microbes Infect. 2019.
PMID: 30866783
Free PMC article.
In vitro inhibition of African swine fever virus-topoisomerase II disrupts viral replication.
Freitas FB, Frouco G, Martins C, Leitão A, Ferreira F.
Freitas FB, et al. Among authors: frouco g.
Antiviral Res. 2016 Oct;134:34-41. doi: 10.1016/j.antiviral.2016.08.021. Epub 2016 Aug 26.
Antiviral Res. 2016.
PMID: 27568922
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DNA-Binding Properties of African Swine Fever Virus pA104R, a Histone-Like Protein Involved in Viral Replication and Transcription.
Frouco G, Freitas FB, Coelho J, Leitão A, Martins C, Ferreira F.
Frouco G, et al.
J Virol. 2017 May 26;91(12):e02498-16. doi: 10.1128/JVI.02498-16. Print 2017 Jun 15.
J Virol. 2017.
PMID: 28381576
Free PMC article.
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Sodium phenylbutyrate abrogates African swine fever virus replication by disrupting the virus-induced hypoacetylation status of histone H3K9/K14.
Frouco G, Freitas FB, Martins C, Ferreira F.
Frouco G, et al.
Virus Res. 2017 Oct 15;242:24-29. doi: 10.1016/j.virusres.2017.09.009. Epub 2017 Sep 13.
Virus Res. 2017.
PMID: 28916365
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African swine fever virus encodes for an E2-ubiquitin conjugating enzyme that is mono- and di-ubiquitinated and required for viral replication cycle.
Freitas FB, Frouco G, Martins C, Ferreira F.
Freitas FB, et al. Among authors: frouco g.
Sci Rep. 2018 Feb 22;8(1):3471. doi: 10.1038/s41598-018-21872-2.
Sci Rep. 2018.
PMID: 29472632
Free PMC article.
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Towards the Generation of an ASFV-pA104R DISC Mutant and a Complementary Cell Line-A Potential Methodology for the Production of a Vaccine Candidate.
Freitas FB, Simões M, Frouco G, Martins C, Ferreira F.
Freitas FB, et al. Among authors: frouco g.
Vaccines (Basel). 2019 Jul 18;7(3):68. doi: 10.3390/vaccines7030068.
Vaccines (Basel). 2019.
PMID: 31323824
Free PMC article.
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