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Ghrelin enhances appetite and increases food intake in humans.
Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR. Wren AM, et al. Among authors: frost gs. J Clin Endocrinol Metab. 2001 Dec;86(12):5992. doi: 10.1210/jcem.86.12.8111. J Clin Endocrinol Metab. 2001. PMID: 11739476 Free article. Clinical Trial.
Ghrelin stimulates insulin-induced glucose uptake in adipocytes.
Patel AD, Stanley SA, Murphy KG, Frost GS, Gardiner JV, Kent AS, White NE, Ghatei MA, Bloom SR. Patel AD, et al. Among authors: frost gs. Regul Pept. 2006 Mar 15;134(1):17-22. doi: 10.1016/j.regpep.2005.11.001. Epub 2005 Dec 9. Regul Pept. 2006. PMID: 16338009
Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased energy expenditure and amelioration of hyperglycemia.
Tan TM, Field BC, McCullough KA, Troke RC, Chambers ES, Salem V, Gonzalez Maffe J, Baynes KC, De Silva A, Viardot A, Alsafi A, Frost GS, Ghatei MA, Bloom SR. Tan TM, et al. Diabetes. 2013 Apr;62(4):1131-8. doi: 10.2337/db12-0797. Epub 2012 Dec 17. Diabetes. 2013. PMID: 23248172 Free PMC article. Clinical Trial.
Hepcidin levels in diabetes mellitus and polycystic ovary syndrome.
Sam AH, Busbridge M, Amin A, Webber L, White D, Franks S, Martin NM, Sleeth M, Ismail NA, Daud NM, Papamargaritis D, Le Roux CW, Chapman RS, Frost G, Bloom SR, Murphy KG. Sam AH, et al. Among authors: frost g. Diabet Med. 2013 Dec;30(12):1495-9. doi: 10.1111/dme.12262. Epub 2013 Aug 19. Diabet Med. 2013. PMID: 23796160 Free PMC article.
The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism.
Frost G, Sleeth ML, Sahuri-Arisoylu M, Lizarbe B, Cerdan S, Brody L, Anastasovska J, Ghourab S, Hankir M, Zhang S, Carling D, Swann JR, Gibson G, Viardot A, Morrison D, Louise Thomas E, Bell JD. Frost G, et al. Nat Commun. 2014 Apr 29;5:3611. doi: 10.1038/ncomms4611. Nat Commun. 2014. PMID: 24781306 Free PMC article.
575 results