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HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival.
Suleman S, Payne A, Bowden J, Haque SA, Zahn M, Fawaz S, Khalifa MS, Jobling S, Hay D, Franco M, Fronza R, Wang W, Strobel-Freidekind O, Deichmann A, Takeuchi Y, Waddington SN, Gil-Farina I, Schmidt M, Themis M. Suleman S, et al. Among authors: fronza r. Gene Ther. 2022 Dec;29(12):720-729. doi: 10.1038/s41434-022-00335-4. Epub 2022 May 5. Gene Ther. 2022. PMID: 35513551 Free PMC article.
Lentiviral Vector Promoter is Decisive for Aberrant Transcript Formation.
Scholz SJ, Fronza R, Bartholomä CC, Cesana D, Montini E, von Kalle C, Gil-Farina I, Schmidt M. Scholz SJ, et al. Among authors: fronza r. Hum Gene Ther. 2017 Oct;28(10):875-885. doi: 10.1089/hum.2017.162. Epub 2017 Aug 18. Hum Gene Ther. 2017. PMID: 28825370
The Clonal Fate of Live Cells.
Wang W, Fronza R, Schmidt M. Wang W, et al. Among authors: fronza r. Mol Ther Methods Clin Dev. 2017 Apr 14;5:93-95. doi: 10.1016/j.omtm.2017.03.007. eCollection 2017 Jun 16. Mol Ther Methods Clin Dev. 2017. PMID: 28480309 Free PMC article. Review. No abstract available.
A Graph Based Framework to Model Virus Integration Sites.
Fronza R, Vasciaveo A, Benso A, Schmidt M. Fronza R, et al. Comput Struct Biotechnol J. 2015 Nov 30;14:69-77. doi: 10.1016/j.csbj.2015.10.006. eCollection 2016. Comput Struct Biotechnol J. 2015. PMID: 27257470 Free PMC article.
Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs.
Wünsche P, Eckert ESP, Holland-Letz T, Paruzynski A, Hotz-Wagenblatt A, Fronza R, Rath T, Gil-Farina I, Schmidt M, von Kalle C, Klein C, Ball CR, Herbst F, Glimm H. Wünsche P, et al. Among authors: fronza r. Cell Stem Cell. 2018 Jul 5;23(1):132-146.e9. doi: 10.1016/j.stem.2018.06.003. Cell Stem Cell. 2018. PMID: 29979988 Free article.
38 results