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A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Pradas-Juni M, Hansmeier NR, Link JC, Schmidt E, Larsen BD, Klemm P, Meola N, Topel H, Loureiro R, Dhaouadi I, Kiefer CA, Schwarzer R, Khani S, Oliverio M, Awazawa M, Frommolt P, Heeren J, Scheja L, Heine M, Dieterich C, Büning H, Yang L, Cao H, Jesus DF, Kulkarni RN, Zevnik B, Tröder SE, Knippschild U, Edwards PA, Lee RG, Yamamoto M, Ulitsky I, Fernandez-Rebollo E, Vallim TQA, Kornfeld JW. Pradas-Juni M, et al. Among authors: frommolt p. Nat Commun. 2020 Jan 31;11(1):644. doi: 10.1038/s41467-020-14323-y. Nat Commun. 2020. PMID: 32005828 Free PMC article.
LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat.
Schmidt E, Dhaouadi I, Gaziano I, Oliverio M, Klemm P, Awazawa M, Mitterer G, Fernandez-Rebollo E, Pradas-Juni M, Wagner W, Hammerschmidt P, Loureiro R, Kiefer C, Hansmeier NR, Khani S, Bergami M, Heine M, Ntini E, Frommolt P, Zentis P, Ørom UA, Heeren J, Blüher M, Bilban M, Kornfeld JW. Schmidt E, et al. Among authors: frommolt p. Nat Commun. 2018 Sep 6;9(1):3622. doi: 10.1038/s41467-018-05933-8. Nat Commun. 2018. PMID: 30190464 Free PMC article.
Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function.
Oliverio M, Schmidt E, Mauer J, Baitzel C, Hansmeier N, Khani S, Konieczka S, Pradas-Juni M, Brodesser S, Van TM, Bartsch D, Brönneke HS, Heine M, Hilpert H, Tarcitano E, Garinis GA, Frommolt P, Heeren J, Mori MA, Brüning JC, Kornfeld JW. Oliverio M, et al. Among authors: frommolt p. Nat Cell Biol. 2016 Mar;18(3):328-36. doi: 10.1038/ncb3316. Epub 2016 Feb 22. Nat Cell Biol. 2016. PMID: 26900752
Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.
Schrader A, Crispatzu G, Oberbeck S, Mayer P, Pützer S, von Jan J, Vasyutina E, Warner K, Weit N, Pflug N, Braun T, Andersson EI, Yadav B, Riabinska A, Maurer B, Ventura Ferreira MS, Beier F, Altmüller J, Lanasa M, Herling CD, Haferlach T, Stilgenbauer S, Hopfinger G, Peifer M, Brümmendorf TH, Nürnberg P, Elenitoba-Johnson KSJ, Zha S, Hallek M, Moriggl R, Reinhardt HC, Stern MH, Mustjoki S, Newrzela S, Frommolt P, Herling M. Schrader A, et al. Among authors: frommolt p. Nat Commun. 2018 Feb 15;9(1):697. doi: 10.1038/s41467-017-02688-6. Nat Commun. 2018. PMID: 29449575 Free PMC article.
A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.
Kaiser RWJ, Ignarski M, Van Nostrand EL, Frese CK, Jain M, Cukoski S, Heinen H, Schaechter M, Seufert L, Bunte K, Frommolt P, Keller P, Helm M, Bohl K, Höhne M, Schermer B, Benzing T, Höpker K, Dieterich C, Yeo GW, Müller RU, Fabretti F. Kaiser RWJ, et al. Among authors: frommolt p. Sci Rep. 2019 Jul 30;9(1):11071. doi: 10.1038/s41598-019-47552-3. Sci Rep. 2019. PMID: 31363146 Free PMC article.
Intestinal insulin/IGF1 signalling through FoxO1 regulates epithelial integrity and susceptibility to colon cancer.
Ostermann AL, Wunderlich CM, Schneiders L, Vogt MC, Woeste MA, Belgardt BF, Niessen CM, Martiny B, Schauss AC, Frommolt P, Nikolaev A, Hövelmeyer N, Sears RC, Koch PJ, Günzel D, Brüning JC, Wunderlich FT. Ostermann AL, et al. Among authors: frommolt p. Nat Metab. 2019 Mar;1(3):371-389. doi: 10.1038/s42255-019-0037-8. Epub 2019 Mar 4. Nat Metab. 2019. PMID: 32694718
62 results