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Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study, Not Predicted by Standard In Vitro Ion Channel Assays.
Brown AP, Friedrichs GS, Tang HM, Traebert M, Weber V, Yao N, Yan GX. Brown AP, et al. Among authors: friedrichs gs. Int J Toxicol. 2024 Feb 8:10915818241230900. doi: 10.1177/10915818241230900. Online ahead of print. Int J Toxicol. 2024. PMID: 38327194
Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation.
Rossman EI, Cools F, Cordes J, Dhuyvetter D, Doyle JM, Friedrichs GS, Guth B, Neradilek MB, Parish ST, Pierson JB, Polissar N, Tang HM. Rossman EI, et al. Among authors: friedrichs gs. J Pharmacol Toxicol Methods. 2020 Sep;105:106897. doi: 10.1016/j.vascn.2020.106897. Epub 2020 Jul 12. J Pharmacol Toxicol Methods. 2020. PMID: 32663523
An Industry Survey With Focus on Cardiovascular Safety Pharmacology Study Design and Data Interpretation.
Authier S, Abernathy MM, Correll K, Chui RW, Dalton J, Foley CM, Friedrichs GS, Koerner JE, Kallman MJ, Pannirselvam M, Redfern WS, Urmaliya V, Valentin JP, Wisialowski T, Zabka TS, Pugsley MK. Authier S, et al. Among authors: friedrichs gs. Int J Toxicol. 2020 Jul/Aug;39(4):274-293. doi: 10.1177/1091581820921338. Epub 2020 May 14. Int J Toxicol. 2020. PMID: 32406289
89 results