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Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia.
Taylor J, Uhl L, Moll I, Hasan SS, Wiedmann L, Morgenstern J, Giaimo BD, Friedrich T, Alsina-Sanchis E, De Angelis Rigotti F, Mülfarth R, Kaltenbach S, Schenk D, Nickel F, Fleming T, Sprinzak D, Mogler C, Korff T, Billeter AT, Müller-Stich BP, Berriel Diaz M, Borggrefe T, Herzig S, Rohm M, Rodriguez-Vita J, Fischer A. Taylor J, et al. Among authors: friedrich t. Nat Cancer. 2023 Nov;4(11):1544-1560. doi: 10.1038/s43018-023-00622-y. Epub 2023 Sep 25. Nat Cancer. 2023. PMID: 37749321 Free PMC article.
Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics.
Ferrante F, Giaimo BD, Friedrich T, Sugino T, Mertens D, Kugler S, Gahr BM, Just S, Pan L, Bartkuhn M, Potente M, Oswald F, Borggrefe T. Ferrante F, et al. Among authors: friedrich t. Cell Death Dis. 2022 Jul 12;13(7):600. doi: 10.1038/s41419-022-05052-9. Cell Death Dis. 2022. PMID: 35821235 Free PMC article.
The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs.
Herchenröther A, Gossen S, Friedrich T, Reim A, Daus N, Diegmüller F, Leers J, Sani HM, Gerstner S, Schwarz L, Stellmacher I, Szymkowiak LV, Nist A, Stiewe T, Borggrefe T, Mann M, Mackay JP, Bartkuhn M, Borchers A, Lan J, Hake SB. Herchenröther A, et al. Among authors: friedrich t. Nat Commun. 2023 Jan 28;14(1):472. doi: 10.1038/s41467-023-36114-x. Nat Commun. 2023. PMID: 36709316 Free PMC article.
Comprehensive genomic features indicative for Notch responsiveness.
Giaimo BD, Friedrich T, Ferrante F, Bartkuhn M, Borggrefe T. Giaimo BD, et al. Among authors: friedrich t. Nucleic Acids Res. 2024 Apr 22:gkae292. doi: 10.1093/nar/gkae292. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38647081
Medicinal Chemistry of Drugs with N-Oxide Functionalities.
Kobus M, Friedrich T, Zorn E, Burmeister N, Maison W. Kobus M, et al. Among authors: friedrich t. J Med Chem. 2024 Apr 11;67(7):5168-5184. doi: 10.1021/acs.jmedchem.4c00254. Epub 2024 Mar 29. J Med Chem. 2024. PMID: 38549449 Free PMC article. Review.
834 results