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LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma.
Alborzinia H, Chen Z, Yildiz U, Freitas FP, Vogel FCE, Varga JP, Batani J, Bartenhagen C, Schmitz W, Büchel G, Michalke B, Zheng J, Meierjohann S, Girardi E, Espinet E, Flórez AF, Dos Santos AF, Aroua N, Cheytan T, Haenlin J, Schlicker L, Xavier da Silva TN, Przybylla A, Zeisberger P, Superti-Furga G, Eilers M, Conrad M, Fabiano M, Schweizer U, Fischer M, Schulze A, Trumpp A, Friedmann Angeli JP. Alborzinia H, et al. Among authors: friedmann angeli jp. EMBO Mol Med. 2023 Aug 7;15(8):e18014. doi: 10.15252/emmm.202318014. Epub 2023 Jul 12. EMBO Mol Med. 2023. PMID: 37435859 Free PMC article.
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.
Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, Roveri A, Peng X, Porto Freitas F, Seibt T, Mehr L, Aichler M, Walch A, Lamp D, Jastroch M, Miyamoto S, Wurst W, Ursini F, Arnér ESJ, Fradejas-Villar N, Schweizer U, Zischka H, Friedmann Angeli JP, Conrad M. Ingold I, et al. Among authors: friedmann angeli jp. Cell. 2018 Jan 25;172(3):409-422.e21. doi: 10.1016/j.cell.2017.11.048. Epub 2017 Dec 28. Cell. 2018. PMID: 29290465 Free article.
Selenium and GPX4, a vital symbiosis.
Friedmann Angeli JP, Conrad M. Friedmann Angeli JP, et al. Free Radic Biol Med. 2018 Nov 1;127:153-159. doi: 10.1016/j.freeradbiomed.2018.03.001. Epub 2018 Mar 6. Free Radic Biol Med. 2018. PMID: 29522794 Review.
Lipoxygenases-Killers against Their Will?
Friedmann Angeli JP, Conrad M. Friedmann Angeli JP, et al. ACS Cent Sci. 2018 Mar 28;4(3):312-314. doi: 10.1021/acscentsci.8b00077. Epub 2018 Mar 16. ACS Cent Sci. 2018. PMID: 29632874 Free PMC article. No abstract available.
Ferroptosis: The Greasy Side of Cell Death.
Friedmann Angeli JP, Miyamoto S, Schulze A. Friedmann Angeli JP, et al. Chem Res Toxicol. 2019 Mar 18;32(3):362-369. doi: 10.1021/acs.chemrestox.8b00349. Epub 2019 Jan 31. Chem Res Toxicol. 2019. PMID: 30653290 Review.
Emerging aspects in the regulation of ferroptosis.
Nehring H, Meierjohann S, Friedmann Angeli JP. Nehring H, et al. Among authors: friedmann angeli jp. Biochem Soc Trans. 2020 Oct 30;48(5):2253-2259. doi: 10.1042/BST20200523. Biochem Soc Trans. 2020. PMID: 33125483 Review.
31 results