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A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease.
Deane R, Singh I, Sagare AP, Bell RD, Ross NT, LaRue B, Love R, Perry S, Paquette N, Deane RJ, Thiyagarajan M, Zarcone T, Fritz G, Friedman AE, Miller BL, Zlokovic BV. Deane R, et al. Among authors: friedman ae. J Clin Invest. 2012 Apr;122(4):1377-92. doi: 10.1172/JCI58642. Epub 2012 Mar 12. J Clin Invest. 2012. PMID: 22406537 Free PMC article.
SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
Yao H, Hwang JW, Sundar IK, Friedman AE, McBurney MW, Guarente L, Gu W, Kinnula VL, Rahman I. Yao H, et al. Among authors: friedman ae. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L615-24. doi: 10.1152/ajplung.00249.2012. Epub 2013 Sep 13. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 24039251 Free PMC article.
In vivo cardioprotection by S-nitroso-2-mercaptopropionyl glycine.
Nadtochiy SM, Burwell LS, Ingraham CA, Spencer CM, Friedman AE, Pinkert CA, Brookes PS. Nadtochiy SM, et al. Among authors: friedman ae. J Mol Cell Cardiol. 2009 Jun;46(6):960-8. doi: 10.1016/j.yjmcc.2009.01.012. Epub 2009 Feb 3. J Mol Cell Cardiol. 2009. PMID: 19339206 Free PMC article.
67 results