Friedland K - Search Results

1

Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.

El Hamdaoui Y, Zheng F, Fritz N, Ye L, Tran MA, Schwickert K, Schirmeister T, Braeuning A, Lichtenstein D, Hellmich UA, Weikert D, Heinrich M, Treccani G, Schäfer MKE, Nowak G, Nürnberg B, Alzheimer C, Müller CP, Friedland K. El Hamdaoui Y, et al. Among authors: friedland k. Mol Psychiatry. 2022 Dec;27(12):5070-5085. doi: 10.1038/s41380-022-01804-3. Epub 2022 Oct 12. Mol Psychiatry. 2022. PMID: 36224261 Free PMC article.

2

Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure.

Möller D, Banerjee A, Uzuneser TC, Skultety M, Huth T, Plouffe B, Hübner H, Alzheimer C, Friedland K, Müller CP, Bouvier M, Gmeiner P. Möller D, et al. Among authors: friedland k. J Med Chem. 2017 Apr 13;60(7):2908-2929. doi: 10.1021/acs.jmedchem.6b01857. Epub 2017 Mar 22. J Med Chem. 2017. PMID: 28248104

3

Activation of membrane-located Ca²⁺ channels by hop beta acids and their tricyclic transformation products.

Schulz C, Fritz N, Sommer T, Krofta K, Friedland K, Pischetsrieder M. Schulz C, et al. Among authors: friedland k. Food Chem. 2018 Jun 30;252:215-227. doi: 10.1016/j.foodchem.2018.01.073. Epub 2018 Jan 10. Food Chem. 2018. PMID: 29478534

4

Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice.

Pochwat B, Szewczyk B, Kotarska K, Rafało-Ulińska A, Siwiec M, Sowa JE, Tokarski K, Siwek A, Bouron A, Friedland K, Nowak G. Pochwat B, et al. Among authors: friedland k. Front Mol Neurosci. 2018 Dec 12;11:456. doi: 10.3389/fnmol.2018.00456. eCollection 2018. Front Mol Neurosci. 2018. PMID: 30618608 Free PMC article.

5

Antidepressant-like activity of hyperforin and changes in BDNF and zinc levels in mice exposed to chronic unpredictable mild stress.

Szewczyk B, Pochwat B, Muszyńska B, Opoka W, Krakowska A, Rafało-Ulińska A, Friedland K, Nowak G. Szewczyk B, et al. Among authors: friedland k. Behav Brain Res. 2019 Oct 17;372:112045. doi: 10.1016/j.bbr.2019.112045. Epub 2019 Jun 17. Behav Brain Res. 2019. PMID: 31220487

6

Acid sphingomyelinase - a regulator of canonical transient receptor potential channel 6 (TRPC6) activity.

Zeitler S, Ye L, Andreyeva A, Schumacher F, Monti J, Nürnberg B, Nowak G, Kleuser B, Reichel M, Fejtová A, Kornhuber J, Rhein C, Friedland K. Zeitler S, et al. Among authors: friedland k. J Neurochem. 2019 Sep;150(6):678-690. doi: 10.1111/jnc.14823. Epub 2019 Aug 22. J Neurochem. 2019. PMID: 31310676 Free article.

7

Differential allosteric modulation within dopamine D₂R - neurotensin NTS1R and D₂R - serotonin 5-HT_2AR receptor complexes gives bias to intracellular calcium signalling.

Plach M, Schäfer T, Borroto-Escuela DO, Weikert D, Gmeiner P, Fuxe K, Friedland K. Plach M, et al. Among authors: friedland k. Sci Rep. 2019 Nov 8;9(1):16312. doi: 10.1038/s41598-019-52540-8. Sci Rep. 2019. PMID: 31704949 Free PMC article.

8

N1-methylation of adenosine (m¹A) in ND5 mRNA leads to complex I dysfunction in Alzheimer's disease.

Jörg M, Plehn JE, Kristen M, Lander M, Walz L, Lietz C, Wijns J, Pichot F, Rojas-Charry L, Wirtz Martin KM, Ruffini N, Kreim N, Gerber S, Motorin Y, Endres K, Rossmanith W, Methner A, Helm M, Friedland K. Jörg M, et al. Among authors: friedland k. Mol Psychiatry. 2024 Jan 29. doi: 10.1038/s41380-024-02421-y. Online ahead of print. Mol Psychiatry. 2024. PMID: 38287100

9

Hyperforin: To Be or Not to Be an Activator of TRPC(6).

Friedland K, Harteneck C. Friedland K, et al. Rev Physiol Biochem Pharmacol. 2015;169:1-24. doi: 10.1007/112_2015_25. Rev Physiol Biochem Pharmacol. 2015. PMID: 26384487 Review.

10

Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal Systems.

Zeitler S, Schumacher F, Monti J, Anni D, Guhathakurta D, Kleuser B, Friedland K, Fejtová A, Kornhuber J, Rhein C. Zeitler S, et al. Among authors: friedland k. Cells. 2020 Nov 18;9(11):2502. doi: 10.3390/cells9112502. Cells. 2020. PMID: 33218173 Free PMC article.

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