Friedland K - Search Results

1

Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia.

Borroto-Escuela DO, Pintsuk J, Schäfer T, Friedland K, Ferraro L, Tanganelli S, Liu F, Fuxe K. Borroto-Escuela DO, et al. Among authors: friedland k. Ther Adv Psychopharmacol. 2016 Apr;6(2):77-94. doi: 10.1177/2045125316637570. Epub 2016 Mar 10. Ther Adv Psychopharmacol. 2016. PMID: 27141290 Free PMC article. Review.

2

Differential allosteric modulation within dopamine D₂R - neurotensin NTS1R and D₂R - serotonin 5-HT_2AR receptor complexes gives bias to intracellular calcium signalling.

Plach M, Schäfer T, Borroto-Escuela DO, Weikert D, Gmeiner P, Fuxe K, Friedland K. Plach M, et al. Among authors: friedland k. Sci Rep. 2019 Nov 8;9(1):16312. doi: 10.1038/s41598-019-52540-8. Sci Rep. 2019. PMID: 31704949 Free PMC article.

3

Label-free versus conventional cellular assays: Functional investigations on the human histamine H₁ receptor.

Lieb S, Littmann T, Plank N, Felixberger J, Tanaka M, Schäfer T, Krief S, Elz S, Friedland K, Bernhardt G, Wegener J, Ozawa T, Buschauer A. Lieb S, et al. Among authors: friedland k. Pharmacol Res. 2016 Dec;114:13-26. doi: 10.1016/j.phrs.2016.10.010. Epub 2016 Oct 15. Pharmacol Res. 2016. PMID: 27751876

4

Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure.

Möller D, Banerjee A, Uzuneser TC, Skultety M, Huth T, Plouffe B, Hübner H, Alzheimer C, Friedland K, Müller CP, Bouvier M, Gmeiner P. Möller D, et al. Among authors: friedland k. J Med Chem. 2017 Apr 13;60(7):2908-2929. doi: 10.1021/acs.jmedchem.6b01857. Epub 2017 Mar 22. J Med Chem. 2017. PMID: 28248104

5

Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.

El Hamdaoui Y, Zheng F, Fritz N, Ye L, Tran MA, Schwickert K, Schirmeister T, Braeuning A, Lichtenstein D, Hellmich UA, Weikert D, Heinrich M, Treccani G, Schäfer MKE, Nowak G, Nürnberg B, Alzheimer C, Müller CP, Friedland K. El Hamdaoui Y, et al. Among authors: friedland k. Mol Psychiatry. 2022 Dec;27(12):5070-5085. doi: 10.1038/s41380-022-01804-3. Epub 2022 Oct 12. Mol Psychiatry. 2022. PMID: 36224261 Free PMC article.

6

Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress.

Menges S, Minakaki G, Schaefer PM, Meixner H, Prots I, Schlötzer-Schrehardt U, Friedland K, Winner B, Outeiro TF, Winklhofer KF, von Arnim CA, Xiang W, Winkler J, Klucken J. Menges S, et al. Among authors: friedland k. Sci Rep. 2017 Feb 22;7:42942. doi: 10.1038/srep42942. Sci Rep. 2017. PMID: 28224980 Free PMC article.

7

Modulation of mitochondrial dysfunction in neurodegenerative diseases via activation of nuclear factor erythroid-2-related factor 2 by food-derived compounds.

Denzer I, Münch G, Friedland K. Denzer I, et al. Among authors: friedland k. Pharmacol Res. 2016 Jan;103:80-94. doi: 10.1016/j.phrs.2015.11.019. Epub 2015 Nov 25. Pharmacol Res. 2016. PMID: 26626189 Review.

8

Acid sphingomyelinase - a regulator of canonical transient receptor potential channel 6 (TRPC6) activity.

Zeitler S, Ye L, Andreyeva A, Schumacher F, Monti J, Nürnberg B, Nowak G, Kleuser B, Reichel M, Fejtová A, Kornhuber J, Rhein C, Friedland K. Zeitler S, et al. Among authors: friedland k. J Neurochem. 2019 Sep;150(6):678-690. doi: 10.1111/jnc.14823. Epub 2019 Aug 22. J Neurochem. 2019. PMID: 31310676 Free article.

9

Pharmacological characterization of high-affinity σ₁ receptor ligands with spirocyclic thienopyran and thienofuran scaffold.

Schepmann D, Neue C, Westphälinger S, Müller C, Bracher F, Lange C, Bednarski P, Almansa C, Friedland K, Räbiger V, Düfer M, Wünsch B. Schepmann D, et al. Among authors: friedland k. J Pharm Pharmacol. 2020 Feb;72(2):236-248. doi: 10.1111/jphp.13196. Epub 2019 Nov 19. J Pharm Pharmacol. 2020. PMID: 31743446

10

Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal Systems.

Zeitler S, Schumacher F, Monti J, Anni D, Guhathakurta D, Kleuser B, Friedland K, Fejtová A, Kornhuber J, Rhein C. Zeitler S, et al. Among authors: friedland k. Cells. 2020 Nov 18;9(11):2502. doi: 10.3390/cells9112502. Cells. 2020. PMID: 33218173 Free PMC article.

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