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Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity.
Nordqvist A, O'Mahony G, Fridén-Saxin M, Fredenwall M, Hogner A, Granberg KL, Aagaard A, Bäckström S, Gunnarsson A, Kaminski T, Xue Y, Dellsén A, Hansson E, Hansson P, Ivarsson I, Karlsson U, Bamberg K, Hermansson M, Georgsson J, Lindmark B, Edman K. Nordqvist A, et al. Among authors: friden saxin m. ChemMedChem. 2017 Jan 5;12(1):50-65. doi: 10.1002/cmdc.201600529. Epub 2016 Dec 15. ChemMedChem. 2017. PMID: 27897427
Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition.
Kennedy AJ, Sundström L, Geschwindner S, Poon EKY, Jiang Y, Chen R, Cooke R, Johnstone S, Madin A, Lim J, Liu Q, Lohman RJ, Nordqvist A, Fridén-Saxin M, Yang W, Brown DG, Fairlie DP, Dekker N. Kennedy AJ, et al. Among authors: friden saxin m. Commun Biol. 2020 Dec 17;3(1):782. doi: 10.1038/s42003-020-01504-0. Commun Biol. 2020. PMID: 33335291 Free PMC article.
Chroman-4-one and chromone based somatostatin β-turn mimetics.
Fridén-Saxin M, Seifert T, Malo M, da Silva Andersson K, Pemberton N, Dyrager C, Friberg A, Dahlén K, Wallén EA, Grøtli M, Luthman K. Fridén-Saxin M, et al. Eur J Med Chem. 2016 May 23;114:59-64. doi: 10.1016/j.ejmech.2016.02.046. Epub 2016 Feb 21. Eur J Med Chem. 2016. PMID: 26974375
KHMDS enhanced SmI(2)-mediated reformatsky type alpha-cyanation.
Ankner T, Fridén-Saxin M, Pemberton N, Seifert T, Grøtli M, Luthman K, Hilmersson G. Ankner T, et al. Among authors: friden saxin m. Org Lett. 2010 May 21;12(10):2210-3. doi: 10.1021/ol100424y. Org Lett. 2010. PMID: 20429501