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Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication.
Schnell L, Felix I, Müller B, Sadi M, von Bank F, Papatheodorou P, Popoff MR, Aktories K, Waltenberger E, Benz R, Weichbrodt C, Fauler M, Frick M, Barth H. Schnell L, et al. Among authors: frick m. FASEB J. 2019 Apr;33(4):5755-5771. doi: 10.1096/fj.201802453R. Epub 2019 Jan 30. FASEB J. 2019. PMID: 30699302
In conclusion, Bac should be discussed as a therapeutic option against infections with medically relevant toxin-producing bacteria, including C. difficile and B. anthracis, because it inhibits bacterial growth and neutralizes the secreted toxins.-Schnell, L., Felix, I., Muller, B …
In conclusion, Bac should be discussed as a therapeutic option against infections with medically relevant toxin-producing bacteria, includin …
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.
Schuster M, Schnell L, Feigl P, Birkhofer C, Mohr K, Roeder M, Carle S, Langer S, Tippel F, Buchner J, Fischer G, Hausch F, Frick M, Schwan C, Aktories K, Schiene-Fischer C, Barth H. Schuster M, et al. Among authors: frick m. Sci Rep. 2017 Apr 4;7(1):613. doi: 10.1038/s41598-017-00780-x. Sci Rep. 2017. PMID: 28377614 Free PMC article.
Pulmonary surfactant protein SP-B promotes exocytosis of lamellar bodies in alveolar type II cells.
Martínez-Calle M, Olmeda B, Dietl P, Frick M, Pérez-Gil J. Martínez-Calle M, et al. Among authors: frick m. FASEB J. 2018 Aug;32(8):4600-4611. doi: 10.1096/fj.201701462RR. Epub 2018 Mar 15. FASEB J. 2018. PMID: 29543530
This result implies that SP-B is not only an essential component for the biophysical function of surfactant but is also a central element in the alveolar homeostasis by eliciting autocrine and paracrine cell stimulation.-Martinez-Calle, M., Olmeda, B., Dietl, P., Frick …
This result implies that SP-B is not only an essential component for the biophysical function of surfactant but is also a central element in …
Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock.
Messerer DAC, Denk S, Föhr KJ, Halbgebauer R, Braun CK, Hönes F, Harant J, Fauler M, Frick M, Nußbaum BL, Radermacher P, Hafner S, Huber-Lang MS. Messerer DAC, et al. Among authors: frick m. Mediators Inflamm. 2018 May 29;2018:2052356. doi: 10.1155/2018/2052356. eCollection 2018. Mediators Inflamm. 2018. PMID: 30002598 Free PMC article.
816 results