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Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs.
Fribourg M, Moreno JL, Holloway T, Provasi D, Baki L, Mahajan R, Park G, Adney SK, Hatcher C, Eltit JM, Ruta JD, Albizu L, Li Z, Umali A, Shim J, Fabiato A, MacKerell AD Jr, Brezina V, Sealfon SC, Filizola M, González-Maeso J, Logothetis DE. Fribourg M, et al. Cell. 2011 Nov 23;147(5):1011-23. doi: 10.1016/j.cell.2011.09.055. Cell. 2011. PMID: 22118459 Free PMC article.
G protein-coupled receptor signaling to Kir channels in Xenopus oocytes.
Hatcher-Solis C, Fribourg M, Spyridaki K, Younkin J, Ellaithy A, Xiang G, Liapakis G, Gonzalez-Maeso J, Zhang H, Cui M, Logothetis DE. Hatcher-Solis C, et al. Among authors: fribourg m. Curr Pharm Biotechnol. 2014;15(10):987-95. doi: 10.2174/1389201015666141031111916. Curr Pharm Biotechnol. 2014. PMID: 25374032 Free PMC article. Review.
Interclass GPCR heteromerization affects localization and trafficking.
Toneatti R, Shin JM, Shah UH, Mayer CR, Saunders JM, Fribourg M, Arsenovic PT, Janssen WG, Sealfon SC, López-Giménez JF, Benson DL, Conway DE, González-Maeso J. Toneatti R, et al. Among authors: fribourg m. Sci Signal. 2020 Oct 20;13(654):eaaw3122. doi: 10.1126/scisignal.aaw3122. Sci Signal. 2020. PMID: 33082287 Free PMC article.
Mechanism of PLC-mediated Kir3 current inhibition.
Keselman I, Fribourg M, Felsenfeld DP, Logothetis DE. Keselman I, et al. Among authors: fribourg m. Channels (Austin). 2007 Mar-Apr;1(2):113-23. doi: 10.4161/chan.4321. Epub 2007 Apr 23. Channels (Austin). 2007. PMID: 18690019
59 results