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FOXA2 controls the anti-oxidant response in FH-deficient cells.
Rogerson C, Sciacovelli M, Maddalena LA, Pouikli A, Segarra-Mondejar M, Valcarcel-Jimenez L, Schmidt C, Yang M, Ivanova E, Kent J, Mora A, Cheeseman D, Carroll JS, Kelsey G, Frezza C. Rogerson C, et al. Among authors: frezza c. Cell Rep. 2023 Jul 25;42(7):112751. doi: 10.1016/j.celrep.2023.112751. Epub 2023 Jul 4. Cell Rep. 2023. PMID: 37405921 Free PMC article.
Metabolic control of antitumor immunity.
Pouikli A, Frezza C. Pouikli A, et al. Among authors: frezza c. Science. 2023 Sep 22;381(6664):1287-1288. doi: 10.1126/science.adk1785. Epub 2023 Sep 21. Science. 2023. PMID: 37733861
Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke.
Mottahedin A, Prag HA, Dannhorn A, Mair R, Schmidt C, Yang M, Sorby-Adams A, Lee JJ, Burger N, Kulaveerasingam D, Huang MM, Pluchino S, Peruzzotti-Jametti L, Goodwin R, Frezza C, Murphy MP, Krieg T. Mottahedin A, et al. Among authors: frezza c. Redox Biol. 2023 Feb;59:102600. doi: 10.1016/j.redox.2023.102600. Epub 2023 Jan 2. Redox Biol. 2023. PMID: 36630820 Free PMC article.
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.
Serrano-Benitez A, Wells SE, Drummond-Clarke L, Russo LC, Thomas JC, Leal GA, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, Jackson SP, Caldecott KW. Serrano-Benitez A, et al. Among authors: frezza c. EMBO J. 2023 Sep 18;42(18):e113190. doi: 10.15252/embj.2022113190. Epub 2023 Jul 26. EMBO J. 2023. PMID: 37492888 Free PMC article.
Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease.
Jones RE, Gruszczyk AV, Schmidt C, Hammersley DJ, Mach L, Lee M, Wong J, Yang M, Hatipoglu S, Lota AS, Barnett SN, Toscano-Rivalta R, Owen R, Raja S, De Robertis F, Smail H, De-Souza A, Stock U, Kellman P, Griffin J, Dumas ME, Martin JL, Saeb-Parsy K, Vazir A, Cleland JGF, Pennell DJ, Bhudia SK, Halliday BP, Noseda M, Frezza C, Murphy MP, Prasad SK. Jones RE, et al. Among authors: frezza c. Nat Cardiovasc Res. 2023;2(8):733-745. doi: 10.1038/s44161-023-00312-z. Epub 2023 Aug 7. Nat Cardiovasc Res. 2023. PMID: 38666037 Free PMC article.
Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.
Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA 3rd, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A. Clerici S, et al. Among authors: frezza c. EMBO Mol Med. 2024 Apr 29. doi: 10.1038/s44321-024-00071-9. Online ahead of print. EMBO Mol Med. 2024. PMID: 38684863 Free article.
Presenting metabolomics analyses: what's in a number?
Meiser J, Frezza C. Meiser J, et al. Among authors: frezza c. EMBO J. 2024 Apr 25. doi: 10.1038/s44318-024-00098-1. Online ahead of print. EMBO J. 2024. PMID: 38664540 Free article. No abstract available.
A glycolytic metabolite bypasses "two-hit" tumor suppression by BRCA2.
Kong LR, Gupta K, Wu AJ, Perera D, Ivanyi-Nagy R, Ahmed SM, Tan TZ, Tan SL, Fuddin A, Sundaramoorthy E, Goh GS, Wong RTX, Costa ASH, Oddy C, Wong H, Patro CPK, Kho YS, Huang XZ, Choo J, Shehata M, Lee SC, Goh BC, Frezza C, Pitt JJ, Venkitaraman AR. Kong LR, et al. Among authors: frezza c. Cell. 2024 Apr 25;187(9):2269-2287.e16. doi: 10.1016/j.cell.2024.03.006. Epub 2024 Apr 11. Cell. 2024. PMID: 38608703 Free article.
232 results