Freywald T - Search Results

1

EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours.

Toosi BM, El Zawily A, Truitt L, Shannon M, Allonby O, Babu M, DeCoteau J, Mousseau D, Ali M, Freywald T, Gall A, Vizeacoumar FS, Kirzinger MW, Geyer CR, Anderson DH, Kim T, Welm AL, Siegel P, Vizeacoumar FJ, Kusalik A, Freywald A. Toosi BM, et al. Among authors: freywald t. Oncogene. 2018 Jul;37(30):4073-4093. doi: 10.1038/s41388-018-0228-x. Epub 2018 Apr 27. Oncogene. 2018. PMID: 29700392 Free PMC article.

2

In human leukemia cells ephrin-B-induced invasive activity is supported by Lck and is associated with reassembling of lipid raft signaling complexes.

Jiang G, Freywald T, Webster J, Kozan D, Geyer R, DeCoteau J, Narendran A, Freywald A. Jiang G, et al. Among authors: freywald t, freywald a. Mol Cancer Res. 2008 Feb;6(2):291-305. doi: 10.1158/1541-7786.MCR-07-0047. Mol Cancer Res. 2008. PMID: 18314490

3

The EphB6 receptor cooperates with c-Cbl to regulate the behavior of breast cancer cells.

Truitt L, Freywald T, DeCoteau J, Sharfe N, Freywald A. Truitt L, et al. Among authors: freywald t, freywald a. Cancer Res. 2010 Feb 1;70(3):1141-53. doi: 10.1158/0008-5472.CAN-09-1710. Epub 2010 Jan 19. Cancer Res. 2010. PMID: 20086179

4

EphB receptors trigger Akt activation and suppress Fas receptor-induced apoptosis in malignant T lymphocytes.

Maddigan A, Truitt L, Arsenault R, Freywald T, Allonby O, Dean J, Narendran A, Xiang J, Weng A, Napper S, Freywald A. Maddigan A, et al. Among authors: freywald t. J Immunol. 2011 Dec 1;187(11):5983-94. doi: 10.4049/jimmunol.1003482. Epub 2011 Oct 28. J Immunol. 2011. PMID: 22039307

5

Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction.

Allonby O, El Zawily AM, Freywald T, Mousseau DD, Chlan J, Anderson D, Benmerah A, Sidhu V, Babu M, DeCoteau J, Freywald A. Allonby O, et al. Among authors: freywald t. Cell Signal. 2014 Dec;26(12):2645-57. doi: 10.1016/j.cellsig.2014.08.007. Epub 2014 Aug 23. Cell Signal. 2014. PMID: 25152371

6

Yeast mitochondrial protein-protein interactions reveal diverse complexes and disease-relevant functional relationships.

Jin K, Musso G, Vlasblom J, Jessulat M, Deineko V, Negroni J, Mosca R, Malty R, Nguyen-Tran DH, Aoki H, Minic Z, Freywald T, Phanse S, Xiang Q, Freywald A, Aloy P, Zhang Z, Babu M. Jin K, et al. Among authors: freywald t. J Proteome Res. 2015 Feb 6;14(2):1220-37. doi: 10.1021/pr501148q. Epub 2015 Jan 20. J Proteome Res. 2015. PMID: 25546499

7

Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining.

Jessulat M, Malty RH, Nguyen-Tran DH, Deineko V, Aoki H, Vlasblom J, Omidi K, Jin K, Minic Z, Hooshyar M, Burnside D, Samanfar B, Phanse S, Freywald T, Prasad B, Zhang Z, Vizeacoumar F, Krogan NJ, Freywald A, Golshani A, Babu M. Jessulat M, et al. Among authors: freywald t. Mol Cell Biol. 2015 Jul;35(14):2448-63. doi: 10.1128/MCB.00007-15. Epub 2015 May 11. Mol Cell Biol. 2015. PMID: 25963654 Free PMC article.

8

Targeting synthetic lethality between the SRC kinase and the EPHB6 receptor may benefit cancer treatment.

Paul JM, Toosi B, Vizeacoumar FS, Bhanumathy KK, Li Y, Gerger C, El Zawily A, Freywald T, Anderson DH, Mousseau D, Kanthan R, Zhang Z, Vizeacoumar FJ, Freywald A. Paul JM, et al. Among authors: freywald t. Oncotarget. 2016 Aug 2;7(31):50027-50042. doi: 10.18632/oncotarget.10569. Oncotarget. 2016. PMID: 27418135 Free PMC article.

9

The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation.

El Zawily AM, Toosi BM, Freywald T, Indukuri VV, Vizeacoumar FJ, Leary SC, Freywald A. El Zawily AM, et al. Among authors: freywald t. Oncotarget. 2016 Nov 22;7(47):77865-77877. doi: 10.18632/oncotarget.12838. Oncotarget. 2016. PMID: 27788485 Free PMC article.

10

The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment.

El Zawily A, McEwen E, Toosi B, Vizeacoumar FS, Freywald T, Vizeacoumar FJ, Freywald A. El Zawily A, et al. Among authors: freywald t. Sci Rep. 2017 Nov 7;7(1):14767. doi: 10.1038/s41598-017-15200-3. Sci Rep. 2017. PMID: 29116180 Free PMC article.

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