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Dynamic conformational changes of a tardigrade group-3 late embryogenesis abundant protein modulate membrane biophysical properties.
Li XH, Yu CWH, Gomez-Navarro N, Stancheva V, Zhu H, Murthy A, Wozny M, Malhotra K, Johnson CM, Blackledge M, Santhanam B, Liu W, Huang J, Freund SMV, Miller EA, Babu MM. Li XH, et al. Among authors: freund smv. PNAS Nexus. 2024 Jan 18;3(1):pgae006. doi: 10.1093/pnasnexus/pgae006. eCollection 2024 Jan. PNAS Nexus. 2024. PMID: 38269070 Free PMC article.
Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B.
Fatalska A, Hodgson G, Freund SMV, Maslen SL, Morgan T, Thorkelsson SR, van Slegtenhorst M, Lorenz S, Andreeva A, Kaat LD, Bertolotti A. Fatalska A, et al. Among authors: freund smv. Mol Cell. 2024 Feb 1;84(3):506-521.e11. doi: 10.1016/j.molcel.2023.12.011. Epub 2023 Dec 29. Mol Cell. 2024. PMID: 38159565 Free PMC article.
Disease-specific tau filaments assemble via polymorphic intermediates.
Lövestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW. Lövestam S, et al. Among authors: freund smv. Nature. 2024 Jan;625(7993):119-125. doi: 10.1038/s41586-023-06788-w. Epub 2023 Nov 29. Nature. 2024. PMID: 38030728 Free PMC article.
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
Nixon-Abell J, Ruggeri FS, Qamar S, Herling TW, Czekalska MA, Shen Y, Wang G, King C, Fernandopulle MS, Sneideris T, Watson JL, Pillai VVS, Meadows W, Henderson JW, Chambers JE, Wagstaff JL, Williams SH, Coyle H, Lu Y, Zhang S, Marciniak SJ, Freund SMV, Derivery E, Ward ME, Vendruscolo M, Knowles TPJ, St George-Hyslop P. Nixon-Abell J, et al. Among authors: freund smv. bioRxiv [Preprint]. 2023 Mar 24:2023.03.22.533832. doi: 10.1101/2023.03.22.533832. bioRxiv. 2023. PMID: 36993242 Free PMC article. Preprint.
Dynamics in Fip1 regulate eukaryotic mRNA 3' end processing.
Kumar A, Yu CWH, Rodríguez-Molina JB, Li XH, Freund SMV, Passmore LA. Kumar A, et al. Among authors: freund smv. Genes Dev. 2021 Nov 1;35(21-22):1510-1526. doi: 10.1101/gad.348671.121. Epub 2021 Sep 30. Genes Dev. 2021. PMID: 34593603 Free PMC article.
Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Fischer ES, Yu CWH, Bellini D, McLaughlin SH, Orr CM, Wagner A, Freund SMV, Barford D. Fischer ES, et al. Among authors: freund smv. EMBO Rep. 2021 Jul 5;22(7):e52242. doi: 10.15252/embr.202052242. Epub 2021 May 19. EMBO Rep. 2021. PMID: 34013668 Free PMC article.
78 results