Freudenreich CH - Search Results

1

The RNA export and RNA decay complexes THO and TRAMP prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions.

Brown RE, Su XA, Fair S, Wu K, Verra L, Jong R, Andrykovich K, Freudenreich CH. Brown RE, et al. Among authors: freudenreich ch. PLoS Biol. 2022 Dec 27;20(12):e3001940. doi: 10.1371/journal.pbio.3001940. eCollection 2022 Dec. PLoS Biol. 2022. PMID: 36574440 Free PMC article.

2

New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.

Gellon L, Razidlo DF, Gleeson O, Verra L, Schulz D, Lahue RS, Freudenreich CH. Gellon L, et al. Among authors: freudenreich ch. PLoS Genet. 2011 Feb 10;7(2):e1001298. doi: 10.1371/journal.pgen.1001298. PLoS Genet. 2011. PMID: 21347277 Free PMC article.

3

Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability.

Su XA, Dion V, Gasser SM, Freudenreich CH. Su XA, et al. Among authors: freudenreich ch. Genes Dev. 2015 May 15;29(10):1006-17. doi: 10.1101/gad.256404.114. Epub 2015 May 4. Genes Dev. 2015. PMID: 25940904 Free PMC article.

4

Relocalization of DNA lesions to the nuclear pore complex.

Freudenreich CH, Su XA. Freudenreich CH, et al. FEMS Yeast Res. 2016 Dec 1;16(8):fow095. doi: 10.1093/femsyr/fow095. FEMS Yeast Res. 2016. PMID: 27799300 Free PMC article. Review.

5

Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats.

Nguyen JHG, Viterbo D, Anand RP, Verra L, Sloan L, Richard GF, Freudenreich CH. Nguyen JHG, et al. Among authors: freudenreich ch. Nucleic Acids Res. 2017 May 5;45(8):4519-4531. doi: 10.1093/nar/gkx088. Nucleic Acids Res. 2017. PMID: 28175398 Free PMC article.

6

Cytosine deamination and base excision repair cause R-loop-induced CAG repeat fragility and instability in Saccharomyces cerevisiae.

Su XA, Freudenreich CH. Su XA, et al. Among authors: freudenreich ch. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8392-E8401. doi: 10.1073/pnas.1711283114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923949 Free PMC article.

7

The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae.

Koch MR, House NCM, Cosetta CM, Jong RM, Salomon CG, Joyce CE, Philips EA, Su XA, Freudenreich CH. Koch MR, et al. Among authors: freudenreich ch. Genetics. 2018 Mar;208(3):963-976. doi: 10.1534/genetics.117.300529. Epub 2018 Jan 5. Genetics. 2018. PMID: 29305386 Free PMC article.

8

Structure-forming repeats and their impact on genome stability.

Brown RE, Freudenreich CH. Brown RE, et al. Among authors: freudenreich ch. Curr Opin Genet Dev. 2021 Apr;67:41-51. doi: 10.1016/j.gde.2020.10.006. Epub 2020 Dec 3. Curr Opin Genet Dev. 2021. PMID: 33279816 Free PMC article. Review.

9

Restarted replication forks are error-prone and cause CAG repeat expansions and contractions.

Gold MA, Whalen JM, Freon K, Hong Z, Iraqui I, Lambert SAE, Freudenreich CH. Gold MA, et al. Among authors: freudenreich ch. PLoS Genet. 2021 Oct 21;17(10):e1009863. doi: 10.1371/journal.pgen.1009863. eCollection 2021 Oct. PLoS Genet. 2021. PMID: 34673780 Free PMC article.

10

Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility.

Callahan JL, Andrews KJ, Zakian VA, Freudenreich CH. Callahan JL, et al. Among authors: freudenreich ch. Mol Cell Biol. 2003 Nov;23(21):7849-60. doi: 10.1128/MCB.23.21.7849-7860.2003. Mol Cell Biol. 2003. PMID: 14560028 Free PMC article.

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