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RhoA Signaling in Neurodegenerative Diseases.
Schmidt SI, Blaabjerg M, Freude K, Meyer M. Schmidt SI, et al. Among authors: freude k. Cells. 2022 May 1;11(9):1520. doi: 10.3390/cells11091520. Cells. 2022. PMID: 35563826 Free PMC article. Review.
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B.
Zhang Y, Schmid B, Nikolaisen NK, Rasmussen MA, Aldana BI, Agger M, Calloe K, Stummann TC, Larsen HM, Nielsen TT, Huang J, Xu F, Liu X, Bolund L, Meyer M, Bak LK, Waagepetersen HS, Luo Y, Nielsen JE; FReJA Consortium; Holst B, Clausen C, Hyttel P, Freude KK. Zhang Y, et al. Among authors: freude kk. Stem Cell Reports. 2017 Mar 14;8(3):648-658. doi: 10.1016/j.stemcr.2017.01.012. Epub 2017 Feb 16. Stem Cell Reports. 2017. PMID: 28216144 Free PMC article.
Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells.
Schmidt SI, Bogetofte H, Ritter L, Agergaard JB, Hammerich D, Kabiljagic AA, Wlodarczyk A, Lopez SG, Sørensen MD, Jørgensen ML, Okarmus J, Serrano AM, Kristensen BW, Freude K, Owens T, Meyer M. Schmidt SI, et al. Among authors: freude k. Stem Cell Reports. 2021 Feb 9;16(2):281-294. doi: 10.1016/j.stemcr.2020.12.011. Epub 2021 Jan 21. Stem Cell Reports. 2021. PMID: 33482100 Free PMC article.
Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.
Chandrasekaran A, Dittlau KS, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TT, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D, Gorodkin J, Muddashetty RS, Meyer M, Aldana BI, Freude KK. Chandrasekaran A, et al. Among authors: freude kk. Stem Cell Reports. 2021 Nov 9;16(11):2736-2751. doi: 10.1016/j.stemcr.2021.09.013. Epub 2021 Oct 21. Stem Cell Reports. 2021. PMID: 34678206 Free PMC article.
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms.
Stoklund Dittlau K, Terrie L, Baatsen P, Kerstens A, De Swert L, Janky R, Corthout N, Masrori P, Van Damme P, Hyttel P, Meyer M, Thorrez L, Freude K, Van Den Bosch L. Stoklund Dittlau K, et al. Among authors: freude k. Mol Neurodegener. 2023 Jan 18;18(1):5. doi: 10.1186/s13024-022-00591-3. Mol Neurodegener. 2023. PMID: 36653804 Free PMC article.
Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer's disease neurons.
Haukedal H, Corsi GI, Gadekar VP, Doncheva NT, Kedia S, de Haan N, Chandrasekaran A, Jensen P, Schiønning P, Vallin S, Marlet FR, Poon A, Pires C, Agha FK, Wandall HH, Cirera S, Simonsen AH, Nielsen TT, Nielsen JE, Hyttel P, Muddashetty R, Aldana BI, Gorodkin J, Nair D, Meyer M, Larsen MR, Freude K. Haukedal H, et al. Among authors: freude k. Front Neurosci. 2023 Feb 16;17:1120086. doi: 10.3389/fnins.2023.1120086. eCollection 2023. Front Neurosci. 2023. PMID: 36875643 Free PMC article.
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3.
Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, Aldana BI, Freude K. Haukedal H, et al. Among authors: freude k. Brain Behav Immun. 2023 Oct;113:353-373. doi: 10.1016/j.bbi.2023.07.024. Epub 2023 Aug 3. Brain Behav Immun. 2023. PMID: 37543250 Free article.
Astrocytes: The Stars in Neurodegeneration?
Stoklund Dittlau K, Freude K. Stoklund Dittlau K, et al. Among authors: freude k. Biomolecules. 2024 Feb 28;14(3):289. doi: 10.3390/biom14030289. Biomolecules. 2024. PMID: 38540709 Free PMC article. Review.
96 results