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Neural network extrapolation to distant regions of the protein fitness landscape.
bioRxiv [Preprint]. 2023 Nov 9:2023.11.08.566287. doi: 10.1101/2023.11.08.566287.
bioRxiv. 2023.
PMID: 37987009
Free PMC article.
Preprint.
Inferring protein fitness landscapes from laboratory evolution experiments.
D'Costa S, Hinds EC, Freschlin CR, Song H, Romero PA.
D'Costa S, et al. Among authors: freschlin cr.
PLoS Comput Biol. 2023 Mar 1;19(3):e1010956. doi: 10.1371/journal.pcbi.1010956. eCollection 2023 Mar.
PLoS Comput Biol. 2023.
PMID: 36857380
Free PMC article.
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Activation of MAP2K signaling by genetic engineering or HF-rTMS promotes corticospinal axon sprouting and functional regeneration.
Boato F, Guan X, Zhu Y, Ryu Y, Voutounou M, Rynne C, Freschlin CR, Zumbo P, Betel D, Matho K, Makarov SN, Wu Z, Son YJ, Nummenmaa A, Huang JZ, Edwards DJ, Zhong J.
Boato F, et al. Among authors: freschlin cr.
Sci Transl Med. 2023 Jan 4;15(677):eabq6885. doi: 10.1126/scitranslmed.abq6885. Epub 2023 Jan 4.
Sci Transl Med. 2023.
PMID: 36599003
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Machine learning to navigate fitness landscapes for protein engineering.
Freschlin CR, Fahlberg SA, Romero PA.
Freschlin CR, et al.
Curr Opin Biotechnol. 2022 Jun;75:102713. doi: 10.1016/j.copbio.2022.102713. Epub 2022 Apr 9.
Curr Opin Biotechnol. 2022.
PMID: 35413604
Free PMC article.
Review.
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