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Page 1
Diet-Induced Abdominal Obesity, Metabolic Changes, and Atherosclerosis in Hypercholesterolemic Minipigs.
Al-Mashhadi AL, Poulsen CB, von Wachenfeldt K, Robertson AK, Bentzon JF, Nielsen LB, Thygesen J, Tolbod LP, Larsen JR, Moestrup SK, Frendéus B, Mortensen B, Drouet L, Al-Mashhadi RH, Falk E. Al-Mashhadi AL, et al. Among authors: frendeus b. J Diabetes Res. 2018 Feb 25;2018:6823193. doi: 10.1155/2018/6823193. eCollection 2018. J Diabetes Res. 2018. PMID: 29682581 Free PMC article.
Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions.
Poulsen CB, Al-Mashhadi AL, von Wachenfeldt K, Bentzon JF, Nielsen LB, Al-Mashhadi RH, Thygesen J, Tolbod L, Larsen JR, Frøkiær J, Tawakol A, Vucic E, Fredrickson J, Baruch A, Frendéus B, Robertson AK, Moestrup SK, Drouet L, Falk E. Poulsen CB, et al. Among authors: frendeus b. Int J Cardiol. 2016 Jul 15;215:506-15. doi: 10.1016/j.ijcard.2016.03.222. Epub 2016 Apr 2. Int J Cardiol. 2016. PMID: 27135822
Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques.
Li S, Kievit P, Robertson AK, Kolumam G, Li X, von Wachenfeldt K, Valfridsson C, Bullens S, Messaoudi I, Bader L, Cowan KJ, Kamath A, van Bruggen N, Bunting S, Frendéus B, Grove KL. Li S, et al. Among authors: frendeus b. Mol Metab. 2013 Jun 11;2(3):256-69. doi: 10.1016/j.molmet.2013.06.001. eCollection 2013. Mol Metab. 2013. PMID: 24049738 Free PMC article.
Recombinant antibodies to an oxidized low-density lipoprotein epitope induce rapid regression of atherosclerosis in apobec-1(-/-)/low-density lipoprotein receptor(-/-) mice.
Schiopu A, Frendéus B, Jansson B, Söderberg I, Ljungcrantz I, Araya Z, Shah PK, Carlsson R, Nilsson J, Fredrikson GN. Schiopu A, et al. Among authors: frendeus b. J Am Coll Cardiol. 2007 Dec 11;50(24):2313-8. doi: 10.1016/j.jacc.2007.07.081. Epub 2007 Nov 26. J Am Coll Cardiol. 2007. PMID: 18068040 Free article.
FDG-PET imaging for oxidized LDL in stable atherosclerotic disease: a phase II study of safety, tolerability, and anti-inflammatory activity.
Lehrer-Graiwer J, Singh P, Abdelbaky A, Vucic E, Korsgren M, Baruch A, Fredrickson J, van Bruggen N, Tang MT, Frendeus B, Rudd JHF, Hsieh F, Ballantyne CM, Ghoshhajra B, Rosenson RS, Koren M, Roth EM, Duprez DA, Fayad ZA, Tawakol AA. Lehrer-Graiwer J, et al. Among authors: frendeus b. JACC Cardiovasc Imaging. 2015 Apr;8(4):493-494. doi: 10.1016/j.jcmg.2014.06.021. Epub 2014 Nov 12. JACC Cardiovasc Imaging. 2015. PMID: 25457756 Free article. Clinical Trial. No abstract available.
A single-arm, open-label, phase 2 clinical trial evaluating disease response following treatment with BI-505, a human anti-intercellular adhesion molecule-1 monoclonal antibody, in patients with smoldering multiple myeloma.
Wichert S, Juliusson G, Johansson Å, Sonesson E, Teige I, Wickenberg AT, Frendeus B, Korsgren M, Hansson M. Wichert S, et al. Among authors: frendeus b. PLoS One. 2017 Feb 3;12(2):e0171205. doi: 10.1371/journal.pone.0171205. eCollection 2017. PLoS One. 2017. PMID: 28158311 Free PMC article. Clinical Trial.
A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia.
Ljungars A, Mårtensson L, Mattsson J, Kovacek M, Sundberg A, Tornberg UC, Jansson B, Persson N, Emruli VK, Ek S, Jerkeman M, Hansson M, Juliusson G, Ohlin M, Frendéus B, Teige I, Mattsson M. Ljungars A, et al. Among authors: frendeus b. NPJ Precis Oncol. 2018 Sep 3;2:18. doi: 10.1038/s41698-018-0061-2. eCollection 2018. NPJ Precis Oncol. 2018. PMID: 30182064 Free PMC article.
A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
Veitonmäki N, Hansson M, Zhan F, Sundberg A, Löfstedt T, Ljungars A, Li ZC, Martinsson-Niskanen T, Zeng M, Yang Y, Danielsson L, Kovacek M, Lundqvist A, Mårtensson L, Teige I, Tricot G, Frendéus B. Veitonmäki N, et al. Among authors: frendeus b. Cancer Cell. 2013 Apr 15;23(4):502-15. doi: 10.1016/j.ccr.2013.02.026. Cancer Cell. 2013. PMID: 23597564 Free article.
46 results